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Research ArticleBiomechanics

Lumbar Intervertebral Spacer With Cement Augmentation of Endplates and Integrated Screws as a Fixation Device in an Osteoporotic Model: An In Vitro Kinematic and Load-to-Failure Study

Rayshad Oshtory, Jonathan A. Harris, Pavan D. Patel, Belin A. Mirabile and Brandon S. Bucklen
International Journal of Spine Surgery April 2021, 15 (2) 324-333; DOI: https://doi.org/10.14444/8042
Rayshad Oshtory
1Pacific Heights Spine Center, San Francisco, California
MD, MBA
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Jonathan A. Harris
2Musculoskeletal Education and Research Center (MERC), a Division of Globus Medical, Inc, Audubon, Pennsylvania
MS
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Pavan D. Patel
3School of Biomedical Engineering, Science, and Health Systems, Drexel University, Philadelphia, Pennsylvania
BS
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Belin A. Mirabile
4Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana
BS
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Brandon S. Bucklen
2Musculoskeletal Education and Research Center (MERC), a Division of Globus Medical, Inc, Audubon, Pennsylvania
PHD
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  • Figure 1
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    Figure 1

    Representative sagittal fluoroscopic image of investigated anterior lumbar constructs. A. BPS+S; B. PMMA+iSA; C. PMMA+UPS+iS. BPS, bilateral pedicle screws; iS, integrated lateral lumbar interbody spacer; iSA, integrated lateral lumbar interbody spacer without posterior fixation; PMMA, polymethyl methacrylate; S, lateral lumbar interbody spacer; UPS, unilateral pedicle screws.

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    Figure 2

    Representative axial fluoroscopic image of bone cement distribution of disarticulated L4 (left) and L5 (right) following compressive testing. Note that the vertebral body fracture at L4 and cement fragmentation at L5 resulted from failure testing, not the initial application of cement.

  • Figure 3
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    Figure 3

    Range of motion at L4–L5 for treatment groups in all planes of motion. BPS, bilateral pedicle screws; iS, integrated lateral lumbar interbody spacer; iSA, integrated lateral lumbar interbody spacer without posterior fixation; PMMA, polymethyl methacrylate; S, lateral lumbar interbody spacer; UPS, unilateral pedicle screws.

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    Figure 4

    Representative load to failure as defined on force output from compression data.

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    Figure 5

    Ultimate load to failure as function of specimen specific bone mineral density per treatment group. BPS, bilateral pedicle screws; iS, integrated lateral lumbar interbody spacer; iSA, integrated lateral lumbar interbody spacer without posterior fixation; PMMA, polymethyl methacrylate; S, lateral lumbar interbody spacer; UPS, unilateral pedicle screws.

  • Figure 6
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    Figure 6

    Ultimate load to failure per treatment group (mean ± SD). BPS, bilateral pedicle screws; iS, integrated lateral lumbar interbody spacer; iSA, integrated lateral lumbar interbody spacer without posterior fixation; PMMA, polymethyl methacrylate; S, lateral lumbar interbody spacer; UPS, unilateral pedicle screws.

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    Figure 7

    Representative gross photography of L4 endplate following ultimate load-to-failure testing. PMMA, polymethyl methacrylate.

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International Journal of Spine Surgery
Vol. 15, Issue 2
1 Apr 2021
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Lumbar Intervertebral Spacer With Cement Augmentation of Endplates and Integrated Screws as a Fixation Device in an Osteoporotic Model: An In Vitro Kinematic and Load-to-Failure Study
Rayshad Oshtory, Jonathan A. Harris, Pavan D. Patel, Belin A. Mirabile, Brandon S. Bucklen
International Journal of Spine Surgery Apr 2021, 15 (2) 324-333; DOI: 10.14444/8042

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Lumbar Intervertebral Spacer With Cement Augmentation of Endplates and Integrated Screws as a Fixation Device in an Osteoporotic Model: An In Vitro Kinematic and Load-to-Failure Study
Rayshad Oshtory, Jonathan A. Harris, Pavan D. Patel, Belin A. Mirabile, Brandon S. Bucklen
International Journal of Spine Surgery Apr 2021, 15 (2) 324-333; DOI: 10.14444/8042
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Keywords

  • lateral interbody fusion
  • Biomechanics
  • lumbar fusion
  • osteoporosis
  • bone cement
  • load to failure

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