RT Journal Article
SR Electronic
T1 Operative Outcomes After Cervical Diffuse Idiopathic Skeletal Hyperostosis Fracture in the Elderly
JF International Journal of Spine Surgery
JO Int J Spine Surg
FD International Society for the Advancement of Spine Surgery
SP 435
OP 441
DO 10.14444/8252
VO 16
IS 3
A1 Alp Ozpinar
A1 Jennifer L. Perez
A1 Emily Hacker
A1 Nima Alan
A1 Nitin Agarwal
A1 Hansen Deng
A1 David O. Okonkwo
A1 Adam S. Kanter
A1 D. K. Hamilton
YR 2022
UL http://ijssurgery.com//content/16/3/435.abstract
AB Background Cervical diffuse idiopathic skeletal hyperostosis (DISH) fractures are frequently unstable and carry significant risk of neurologic injury and death. Most patients with DISH fractures are elderly (>70 years) with significant comorbidities. We assessed factors that contribute to outcomes in elderly patients with cervical DISH fractures.Methods Elderly patients with cervical DISH fractures from 2008 to 2017 were included in this retrospective multi-institutional cohort study. Predictor variables included injury level, surgical approach, preinjury comorbidities, American Society of Anesthesiologists (ASA) score, American Spinal Injury Association (ASIA) impairment scale grade, preoperative anticoagulation status, and the subaxial cervical spine injury classification system (SLIC) score. Univariate and multivariate analyses were utilized to identify factors associated with 30-day mortality and ambulatory status at discharge.Results A total of 48 patients, mean age 74.7 years old (range 60–96), underwent cervical fixation for DISH fractures. Average SLIC score was 6.30 ± 1.2 (range 5–8), and most frequent fracture level was at C6 to -C7 (31.3%) followed by C7–T1 (25.0%). Forty (83.3%) patients underwent posterior fixation, 7 (14.6%) with anterior fixation, and 1 (2.1%) had combined approach. Ten (20.4%) patients died within 30 days of surgery. Multivariate analysis demonstrated that poorer preoperative ASIA grade (OR 2.35, P = 0.003, CI = 1.33–4.14) and ASA score >3 (P = 0.027) had increased risk of being nonambulatory at discharge. Higher SLIC score was associated with increased 30-day mortality (P = 0.021, CI = 1.20–9.60).Conclusions Cervical DISH fractures can be highly unstable, for which instrumentation and fixation are indicated. Surgical decision-making should focus on preoperative ASIA grade, SLIC score, and ASA score.Clinical Relevance The study is relevant due to an aging poulation predisposed to cervical DISH fractures.Level of Evidence 4.