TY - JOUR T1 - Ten-Year Experience of Skip Anterior Cervical Corpectomy and Fusion JF - International Journal of Spine Surgery JO - Int J Spine Surg DO - 10.14444/8417 SP - 8417 AU - Steve H. Monk AU - Matthew O’Brien AU - Stephen Perle AU - Michael Bohl AU - Frederick Finger AU - Samuel J. Chewning AU - Christopher M. Holland Y1 - 2023/01/11 UR - http://ijssurgery.com//content/early/2023/01/10/8417.abstract N2 - Background Anterior cervical corpectomy and fusion (ACCF) is often required to adequately decompress the spinal cord in patients with multilevel cervical spondylosis. Unfortunately, multilevel corpectomy constructs have high rates of early failure and frequently require supplemental posterior fixation. First described in 2003, skip ACCF (sACCF) is defined by corpectomies above and below an intervening vertebral body, which serves as an additional fixation point to augment biomechanical stability. Subsequent studies report high fusion rates and low construct failure rates secondary to superior biomechanical stability.Objective The goal of this study was to demonstrate the safety and efficacy of sACCF in the largest series published to date.Methods This study was a retrospective case series of all patients who underwent sACCF at a single institution over a 10-year period. Standard demographic and perioperative data were collected. Outcome data included immediate postoperative complications, long-term reoperation, and pre- and postoperative radiographic parameters.Results Forty-five patients underwent sACCF: 42 at C4-C6 and 3 at C5-C7. Mean age was 57.5 years. More than half (64.4%) of patients were smokers. Almost all patients were discharged home, the vast majority (82.2%) within 3 days of surgery. Five patients (11.1%) developed complications during the index hospitalization: 2 C5 palsies and 3 medical complications. Three patients (6.7%) developed instrumentation failure requiring anterior revision and supplemental posterior fixation. There were statistically significant increases in C1-C7 (47.8 vs 41.1, P < 0.001) and C2-C7 lordosis (11.1 vs 5.0, P < 0.001) on postoperative radiographs compared with preoperative imaging. Average follow-up was 21.1 months.Conclusion sACCF can be performed safely with complication rates similar to those reported for multilevel anterior cervical discectomy and fusion or adjacent segment ACCF. It should be considered for patients with multilevel cervical pathology for whom an anterior approach is favored.Clinical Relevance sACCF is an effective surgical technique for multilevel cervical decompression and correction of cervical alignment.Level of Evidence 3. ER -