PT - JOURNAL ARTICLE AU - Dias Pereira Filho, Aécio Rubens AU - Bertolini Mussalem, Matheus Galvão Valadares AU - Baptista, Vinicius Santos AU - Benites, Vinicius de Meldau AU - Uehara, Milton Kiyonory AU - Colaço Aguiar, Nuno Rodolfo AU - Baston, Arthur Cristiano AU - Desideri, Alexandre Vinhal AU - Frota Carneiro Júnior, Francisco Cialdine TI - Safety and Viability of Anterior Lumbar Interbody Fusion in Complex Revision Lumbar Spine Surgeries: Insights From a Case Series of 135 Patients on Transforaminal Lumbar Interbody Fusion/Posterior Lumbar Interbody Fusion Cage Removal AID - 10.14444/8753 DP - 2025 Apr 17 TA - International Journal of Spine Surgery PG - 8753 4099 - https://www.ijssurgery.com/content/early/2025/04/17/8753.short 4100 - https://www.ijssurgery.com/content/early/2025/04/17/8753.full AB - Background Anterior lumbar interbody fusion (ALIF) has emerged as a valuable technique for managing lumbar degenerative conditions and revision surgeries, particularly for addressing complications associated with transforaminal lumbar interbody fusion (TLIF) and posterior lumbar interbody fusion (PLIF) cages. However, there is limited evidence documenting its safety and feasibility in the context of revision procedures involving cage removal.Objective To evaluate intraoperative outcomes of ALIF for TLIF/PLIF cage removal, focusing on complications, surgical times, and blood loss in a substantial case series.Methods This case series analyzed data from 135 patients who underwent ALIF for TLIF/PLIF cage removal between January 2019 and May 2023. Surgical indications included pseudarthrosis, cage migration, and infection. Outcomes assessed included intraoperative complications, surgical duration, and estimated blood loss.Results Of the 135 patients (median age: 47 years, range: 15–78), vascular injuries occurred in only 4 cases, all involving the left iliac vein, and were managed intraoperatively without sequelae. No injuries to retroperitoneal, neural, or organ structures were observed. Median surgical time was 100 minutes (range: 50–210), with most cases resulting in less than 150 mL of blood loss. These findings demonstrate the feasibility of ALIF for managing TLIF/PLIF complications.Conclusion ALIF is a safe and effective option for revision surgeries involving TLIF/PLIF cage removal, offering a low complication profile and manageable intraoperative challenges. A critical factor contributing to these favorable outcomes is the multidisciplinary approach, where the collaboration between access and spine surgeons ensures meticulous handling of anatomical and vascular challenges.Clinical Relevance This study provides valuable data for further prospective research to explore long-term outcomes and refine surgical techniques.Level of Evidence 4.