PT - JOURNAL ARTICLE AU - Olivier Clerk-Lamalice AU - Douglas P. Beall AU - Kevin Ong AU - Morgan P. Lorio TI - ISASS Policy 2018—Vertebral Augmentation: Coverage Indications, Limitations, and/or Medical Necessity AID - 10.14444/5096 DP - 2018 Dec 01 TA - International Journal of Spine Surgery PG - 5096 4099 - http://ijssurgery.com//content/early/2018/12/19/5096.short 4100 - http://ijssurgery.com//content/early/2018/12/19/5096.full AB - The ISASS Policy Statement on vertebral augmentation has the objectives to provide a background and an update with the latest clinical evidence for the international spine community. A SpineLine Panel Review (2010) appropriately recommended an exploration of “the seeming disconnect between the conclusions of … two [Level I] PRCT's and previous experience and data” regarding vertebral augmentation. ISASS responded by supporting a comprehensive meta-analysis to help frame a cogent historical analysis of vertebral augmentation. This ISASS Policy 2018 is based on a thorough literature search for relevant studies, including systematic reviews and meta-analyses, that are subjected to thorough quality appraisal for the purpose of informing public opinion and decision making. Given the abundance of high-quality information, ISASS can confidently advocate that there is strong support for vertebral augmentation in the treatment of symptomatic vertebral compression fractures.