Table 3

Perioperative characteristics

CharacteristicsSTSDUnadjustedIPW
OR (95% CI) P OR (95% CI) P
Ratio (95% CI)Ratio (95% CI)
Whole Cohort
n 50161
 Duration between procedures when staged, da
  Range (median)1–20 (2)-
  Mean (SD)2.9 (2.8)-
 Number of levels fused in ALIF, n (%)
  113 (26.0%)84 (52.2%)Reference<0.001*Reference0.603
  222 (44.0%)68 (42.2%)2.09 (0.98, 4.45)1.42 (0.43, 4.69)
  314 (28.0%)8 (5.0%)11.3 (3.97, 32.20)1.99 (0.52, 7.63)
  41 (2.0%)1 (0.6%)6.46 (0.38, 109.70)0.37 (0.02, 6.72)
 Number of levels fused in PSF
  Range (median)1–16 (8)1–15 (2)2.79 (2.20, 3.54)<0.001*1.29 (0.81, 2.05)0.275
  Mean (SD)9.1 (4.5)3.8 (3.2)
 Combined EBL, mL
  Range (median)25–4000 (1200)25–5100 (350)2.28 (1.61, 3.22)<0.001*1.07 (0.62, 1.83)0.819
  Mean (SD)1220 (891.5)609.2 (710.5)
 Total intraoperative complications, n (%)7 (14.0%)4 (2.5%)6.39 (1.52, 30.83)0.004*2.94 (0.55, 15.74)0.207
LS Cohort
n 4456
 Duration between procedures when staged, da
  Range (median)0–22 (2)-
  Mean (SD)2.9 (2.9)-
 Number of levels fused in ALIF, n (%)
  111 (25.0%)34 (60.7%)Reference<0.001*Reference0.322
  218 (40.9%)17 (30.4%)3.27 (1.27, 8.46)1.05 (0.34, 3.20)
  314 (31.8%)4 (7.1%)10.82 (2.94, 39.80)2.49 (0.59, 10.44)
  41 (2.3%)1 (1.8%)3.09 (0.18, 53.65)0.17 (0.01, 3.14)
 Number of levels fused in PSF
  Range (median)4–16 (8)4–15 (8)1.37 (1.17, 1.62)0.002*1.09 (0.86, 1.39)0.457
  Mean (SD)10 (3.9)7.3 (3.1)
 Combined EBL, m
  Range (median)25–4000 (1300)25–5100 (875)1.31 (0.89, 1.92)0.0880.82 (0.48, 1.40)0.471
  Mean (SD)1351.7 (869)1127.6 (945.4)
 Total intraoperative complications, n (%)6 (13.6%)2 (3.6%)4.26 (0.70, 44.80)0.1334.25 (0.73, 24.92)0.109
  • Abbreviations: ALIF, anterior lumbar interbody fusion; EBL, estimated blood loss; IPW, inverse probability weighting; LS, long segment; PSF, posterior spinal fusion; SD, same day; ST, staged.

  • Note: Intraoperative complications in the whole cohort were recorded in 11 cases (5.2%), with the ST group showed a significantly higher incidence compared with the SD group (OR = 6.4, P = 0.004). In the LS cohort, intraoperative complications were recorded in 8 patients (8%) with no statistically significant difference between ST and SD groups (Table 2).

  • *Signifies P < 0.05.

  • a The median duration between the staged procedures was 2.9 days with a range of 0 to 22 days for the LS and whole cohort.