One-variable and probabilistic sensitivity analyses, Ranges and Distributions.
| One-Variable Sensitivity Analysis | Probabilistic Sensitivity Analysis | |||
|---|---|---|---|---|
| Variable | Lower | Base case | Upper | Distribution (Parameters) |
| Failure | ||||
| CC | 0.028 | 0.043 | 0.060 | Beta (mean=.043, SE=.008) |
| Spacer | 0.020 | 0.027 | 0.036 | Beta (mean=.027,SE=.004) |
| DS | 0.004 | 0.012 | 0.037 | Beta (mean=.012,SE=.008) |
| DS AE rate | 0.022 | 0.054 | 0.099 | Beta (α = 7, β = 122) |
| IRF discharge rate | 0.013 | 0.039 | 0.078 | Beta (α = 5, β = 124) |
| Proportion 1 Level | 0.25 | 0.50 | 0.75 | Triangular (0.25,0.50,0.75) |
| Fusion rate | 0.17 | 0.31 | 0.47 | Beta (α = 11, β = 24) |
| DS after CC failure | 0.80 | 0.90 | 1.00 | Triangular (0.80,0.90,1.00) |
| Utility Increase | ||||
| CC | 0.000 | 0.016 | 0.030 | Fixed |
| Spacer | 0.120 | 0.144 | 0.168 | Normal (0.144, 0.013) |
| DS, 3 mo | 0.154 | 0.181 | 0.207 | Normal (0.181, 0.014) |
| DS, 12 mo | 0.124 | 0.151 | 0.179 | Normal (0.151, 0.014) |