Abstract
Purpose
To evaluate the clinical efficacy, especially the pain reduction, of vertebroplasty and balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures (OVCFs).
Methods
Eighty-six patients with OVCFs were treated with vertebroplasty or balloon kyphoplasty. All patients were followed up for seven–36 months. Visual analog scale (VAS), vertebral height, and local kyphotic angle were evaluated at pre-operation, postoperation, and final follow-up.
Results
The VAS pain score decreased significantly after surgery in both kyphoplasty and vertebroplasty groups (p < 0.001), and the improvement of VAS score had no significant difference between the two groups (p = 0.826). There was a significant difference in the improvement of vertebral height (p < 0.001) and local kyphotic angle (p < 0.001) between the two groups. Improvement of VAS score had no correlation with improvement of vertebral height (vertebroplasty: r = −0.029, p = 0.869; kyphoplasty: r = 0.175, p = 0.219) or local kyphotic angle (vertebroplasty: r = 0.159, p = 0.361; kyphoplasty: r = 0.144, p = 0.312) in either group.
Conclusion
Vertebroplasty and kyphoplasty are effective procedures for the reduction of pain in OVCFs, and they have the same efficient effect on pain reduction. Correction of vertebral height and local kyphosis may have minimal effect on pain reduction.
Similar content being viewed by others
References
Guan HQ, Yang HL, Mei X et al (2012) Early or delayed operation, which is more optimal for kyphoplasty? A retrospective study on cement leakage during kyphoplasty. Injury 43:1698–1703
Galibert P, Deramond H, Rosat P, Le Gars D (1987) Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty (in French). Neurochirurgie 33:166–168
Calmels V, Vallée JN, Rose M, Chiras J (2007) Osteoblastic and mixed spinal metastases: evaluation of the analgesic efficacy of percutaneous vertebroplasty. Am J Neuroradiol 28:570–574
Serra L, Kermani FM, Panagiotopoulos K et al (2007) Vertebroplasty in the treatment of osteoporotic vertebral fractures: results and functional outcome in a series of 175 consecutive patients. Minim Invasive Neurosurg 50:12–17
Yang HL, Zhao L, Liu J et al (2007) Changes of pulmonary function for patients with osteoporotic vertebral compression fractures after kyphoplasty. J Spinal Disord Tech 20(3):221–225
Dong RB, Chen L, Gu Y et al (2009) Improvement in respiratory function after vertebroplasty and kyphoplasty. Int Orthop 33(6):1689–1694
Liu JT, Liao WJ, Tan WC et al (2010) Balloon kyphoplasty versus vertebroplasty for treatment of osteoporotic vertebral compression fracture: a prospective, comparative, and randomized clinical study. Osteoporos Int 21(2):359–364
Robinson Y, Olerud C (2012) Vertebroplasty and kyphoplasty—A systematic review of cement augmentation techniques for osteoporotic vertebral compression fractures compared to standard medical therapy. Maturitas 72:42–49
Ha KY, Lee JS, Kim KW, Chon JS (2006) Percutaneous vertebroplasty for vertebral compression fractures with and without intravertebral clefts. J Bone Joint Surg 88:629–633
Endres S, Badura A (2012) Shield kyphoplasty through a unipedicular approach compared to vertebroplasty and balloon kyphoplasty in osteoporotic thoracolumbar fracture: A prospective randomized study. Orthop Traumatol Surg Res 98(3):334–340
Kim KH, Kuh SU, Chin DK et al (2012) Kyphoplasty Versus Vertebroplasty: Restoration of Vertebral Body Height and Correction of Kyphotic Deformity With Special Attention to the Shape of the Fractured Vertebrae. J Spinal Disord Tech 25(6):338–344
Barr JD, Barr MS, Lemley TJ, McCann RM (2000) Percutaneous vertebroplasty for pain relief and spinal stabilization. Spine 25:923–928
Chen L, Ni CF, Liu YZ et al (2005) Experimental and clinical study on barium used to increase radiopacity of bone cement for vertebroplasty. Chin J Med Imaging Technol 21(7):1085–1088
Ma R, Chow R, Shen FH (2010) Kummell's disease: delayed post-traumatic osteonecrosis of the vertebral body. Eur Spine J 19(7):1065–1070
Kim KT, Suk KS, Kim JM, Lee SH (2003) Delayed vertebral collapse with neurological deficits secondary to osteoporosis. Int Orthop 27(2):65–69
Santiago FR, Abela AP, Alvarez LG et al (2010) Pain and functional outcome after vertebroplasty and kyphoplasty. A comparative study. Eur J Radiol 75(2):e108–e113
Yeh JH, Yang SC, Kao YH et al (2011) Clinical and radiographic evaluation of balloon kyphoplasty using VCFX for osteoporotic vertebral compression fracture. Formos J Musculoskelet Disord 2:94–98
Shah RV (2012) Sacral kyphoplasty for the treatment of painful sacral insufficiency fractures and metastases. Spine J 12:113–120
Yang CT, Hou SM, Hou CH et al (2011) Does the complication rate and treatment effect of balloon kyphoplasty and vertebroplasty differ in countries or specialties of operators? Formos J Musculoskelet Disord 2:79–84
Buchbinder R, Osborne RH, Ebeling PR et al (2009) A randomized trial of vertebroplasty for painful osteoporotic vertebral fractures. N Engl J Med 361:557–568
Kallmes DF, Comstock BA, Heagerty PJ et al (2009) A randomized controlled trial of vertebroplasty for osteoporotic spine fractures. N Engl J Med 361:569–579
Ettinger B, Black DM, Nevitt MC et al (1992) Contribution of vertebral deformities to chronic back pain and disability. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res 7:449–456
Ryan PJ, Blake G, Herd R, Fogelman I (1994) A clinical profile of back pain and disability in patients with spinal osteoporosis. Bone 15:27–30
Symmons DP, Hemert AM, Vandenbroucke JP, Valkenburg HA (1991) A longitudinal study of back pain and radiological changes in the lumbar spines of middle aged women. II. Radiographic findings. Ann Rheum Dis 50:162–166
Acknowledgements
This project was supported by the National Natural Science Foundation of China (No.81071450) and the Jiangsu Province’s Key Provincial Talents Program (No.RC2011102). The authors would like to thank Liang Guo and Hailin Shen of Department of radiology for help with taking x-ray films and measurement.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Dong, R., Chen, L., Tang, T. et al. Pain reduction following vertebroplasty and kyphoplasty. International Orthopaedics (SICOT) 37, 83–87 (2013). https://doi.org/10.1007/s00264-012-1709-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00264-012-1709-0