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Local recurrences in giant cell tumour of bone

Long-term follow up of 31 cases

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Summary. We studied the value of histopathological grading in determining the prognosis of giant cell tumour (osteoclastoma) and the rate of local and distant recurrences in a consecutive series of 31 patients. We found that grading had no prognostic value. Eighteen patients were treated by intralesional curettage and 13 by wide excision. Ten patients (56%), who were all treated by curettage, had local recurrences, but none of the tumours with wide excision recurred (p <0.05). Five (16%) had local recurrences as well as distant metastases, usually to the lungs. The recurrences developed later than an average of 12 years after primary treatment in 3 patients. Wide excision and life-long follow up should be considered in the management of these tumours.

Résumé. Nous avons étudié l’interêt pronostic du classement anatomo-pathologique des tumeurs à cellules géantes (osteoclastomes) et le taux de récidives à long terme, locales et à distance, dans une série consécutive de 31 patients. Le classement anatomo-pathologique n’a eu aucun interêt pronostic. Dix-huit patients furent traités par curetage, alors que 13 patients furent traités par une excision large. Dix patients (56%), tous traités par curetage, récidivèrent localement, alors qu’aucune des tumeurs traitées par excisision large ne récidiva (p <0.05). Cinq patients (16%) récidivèrent localement et à distance, généralement au niveau pulmonaire. Chez 3 patients, la récidive se déclara en moyenne 12 ans après le traitement initial. L’excision large avec suivi à vie est nécessaire dans ces rares cas de tumeur osseuse.

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Accepted: 14 September 1995

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Lausten, G., Jensen, P., Schiødt, T. et al. Local recurrences in giant cell tumour of bone . International Orthopaedics SICOT 20, 172–176 (1996). https://doi.org/10.1007/s002640050057

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