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Predictive validity of preoperative CT scans and the risk of pedicle screw loosening in spinal surgery

  • Orthopaedic Surgery
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Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Introduction

Pedicle screw fixation is the standard technique for the stabilization of the spine, a clinically relevant complication of which is screw loosening. This retrospective study investigates whether preoperative CT scanning can offer a predictor of screw loosening.

Methods

CT-scan attenuation in 365 patients was evaluated to determine the mean bone density of each vertebral body. Screw loosening or dislocation was determined in CT scans postoperatively using the standard radiological criteria.

Results

Forty-five of 365 patients (12.3 %; 24 male, 21 female) suffered postoperative screw loosening (62 of 2038 screws) over a mean follow-up time of 50.8 months. Revision surgeries were necessary in 23 patients (6.3 %). The correlation between decreasing mean CT attenuation in Hounsfield Units (HU) and increasing patient age was significant (p < 0.001). Mean bone density was 116.3 (SD 53.5) HU in cases with screw loosening and 132.7 (SD 41.3) HU in cases in which screws remained fixed. The difference was statistically significant (p = 0.003).

Conclusion

The determination of bone density with preoperative CT scanning can predict the risk of screw loosening and inform the decision to use cement augmentation to reduce the incidence of screw loosening.

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Acknowledgments

The investigation was supported by the work of Nadja Momotow und Lisa Hölscher.

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Authors and Affiliations

  1. Department of Orthopedics and Trauma Surgery, University Hospital of Cologne, Kerpener Strasse 62, 50937, Cologne, Germany

    Jan Bredow, C. K. Boese, J. Siewe, L. Löhrer, K. Zarghooni, P. Eysel & M. J. Scheyerer

  2. Division of Trauma Surgery, Department of Surgery, University Hospital Zurich, Zurich, Switzerland

    C. M. L. Werner

Authors
  1. Jan Bredow
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  2. C. K. Boese
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  3. C. M. L. Werner
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  4. J. Siewe
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  5. L. Löhrer
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  6. K. Zarghooni
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  7. P. Eysel
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  8. M. J. Scheyerer
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Correspondence to Jan Bredow.

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Bredow, J., Boese, C.K., Werner, C.M.L. et al. Predictive validity of preoperative CT scans and the risk of pedicle screw loosening in spinal surgery. Arch Orthop Trauma Surg 136, 1063–1067 (2016). https://doi.org/10.1007/s00402-016-2487-8

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  • DOI: https://doi.org/10.1007/s00402-016-2487-8

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