Clinical StudiesPercutaneous Vertebroplasty for Osteoporotic Compression Fractures: Quantitative Prospective Evaluation of Long-term Outcomes
Section snippets
MATERIALS AND METHODS
Fifty-four symptomatic vertebral compression fractures in 30 patients with senile osteoporosis were treated with PPV by one physician (W.J.O.) over the course of 6 months. This practitioner was experienced in performing PPV and had already performed more than 100 such procedures before the initiation of this study. The study protocol was reviewed and approved by the Institutional Review Board at the medium-sized community hospital where all treatments were performed.
Early Results
Twenty-nine of 30 patients reported pain relief in the hours immediately after the procedure. There were two minor adverse events.
Posttreatment CT scans were obtained within 3 hours in all cases and were assessed for unexpected or undesirable migration of cement, including significant filling of the epidural venous plexus, foraminal veins, or inferior vena cava. A small epidural leak of PMMA (Fig 2) was asymptomatic and did not require intervention or treatment for this radiographic finding.
DISCUSSION
Conventional treatment of vertebral fractures is typically nonoperative, and, until recently, has focused on the alleviation of acute pain with narcotic and nonsteroidal antiinflammatory agents. Pharmacologic intervention to improve bone marrow density has gained widespread acceptance in recent years (31). Because of significant risk caused by comorbid conditions that are common in this elderly patient population, as well as technical difficulty achieving adequate fixation of hardware within
Acknowledgments
Drs. Zoarski and Stallmeyer have received educational honoraria either directly from one or more of the following companies, or through educational stipends from Percutaneous Vertebroplasty courses that were supported by unrestricted educational grants from the following companies: American OsteoMedix, Cook, Kyphon, Parallax Medical, and Stryker. Dr. Zoarski has been a paid consultant for Kyphon.
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From the 2000 SCVIR Annual Meeting.
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These authors have disclosed the existence of a potential conflict of interest.