Hypertension Research
Online ISSN : 1348-4214
Print ISSN : 0916-9636
ISSN-L : 0916-9636
Case Report
A Case of Metastatic Extra-Adrenal Pheochromocytoma 12 Years after Surgery
Shunsuke MORITakafumi OKURAYutaka KITAMIYasunori TAKATAMichitsugu NAKAMURASanae WATANABETakeru IWATAKunio HIWADA
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2002 Volume 25 Issue 1 Pages 141-144

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Abstract

At the age of 53, a 65-year-old man had been diagnosed with extra-adrenal pheochromocytoma in the retroperitoneum and underwent total tumorectomy. Afterward, he had his serum catecholamine periodically measured in an outpatient clinic. In February 1999, 12 years after surgery, he complained of lower left abdominal pain. Computed tomography and magnetic resonance imaging revealed an osteolytic lesion in thoracic vertebrae 11Th (Th 11). Although his basal serum and urine catecholamines were at normal levels, glucagon injection increased blood pressure and plasma catecholamine levels. 131I-metaiodobenzylguanidine (MIBG) scintigraphy was specifically taken up to Th 11. By bone biopsy, the osteolytic lesion in Th 11 was finally diagnosed with metastasis of pheochromocytoma. For post-operative pheochromocytoma, long-term follow-up involving biochemical tests, including serum catecholamines, and MIBG is needed. (Hypertens Res 2002; 25: 141-144)

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© 2002 by the Japanese Society of Hypertension
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