Thoracic radiculopathy represents an uncommon spinal disorder that is frequently overlooked in the evaluation of spinal pain syndromes. Degenerative disc disease and diabetes mellitus may frequently cause radiculopathy at the thoracic level. Electromyography and magnetic resonance imaging are useful in the evaluation of radiculopathy and thoracic spinal pain syndromes. Percutaneous vertebroplasty is a procedure that may be used in the treatment of thoracic spinal pain syndromes. Surgical intervention for thoracic radiculopathy usually is reserved for patients with progressive myelopathy and neurologic compromise.