Vertebral body osteonecrosis without vertebral collapse

Spine (Phila Pa 1976). 2003 Aug 15;28(16):E323-8. doi: 10.1097/01.BRS.0000083322.21140.90.

Abstract

Study design: A case of idiopathic focal vertebral body osteonecrosis without vertebral collapse is reported.

Objectives: To report a rare case of focal vertebral osteonecrosis and to clarify the features of imaging studies.

Summary of background data: There are no previous reports describing focal vertebral body necrosis without collapse in the literature.

Methods: A case report and literature review are presented.

Results: Imaging studies demonstrated: 1) sclerotic change on computed tomography scan; 2) low intensity on T1, high intensity on T2 with clear margin, and no gadolinium enhancement on magnetic resonance imaging; and 3) no uptake on bone scan. Histologic examination revealed empty lacunas, fatty necrosis with vacuolar degeneration, and cell debris compatible with bone marrow necrosis.

Conclusion: Vertebral body osteonecrosis must be considered a possible diagnosis of patients presenting with low intensity on T1, high intensity on T2 with clear margin, and no gadolinium enhancement on magnetic resonance imaging.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Back Pain / etiology
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Osteonecrosis / complications
  • Osteonecrosis / pathology*
  • Osteosclerosis / pathology
  • Spine / pathology*