Percutaneous transforaminal lumbar interbody fusion for the treatment of degenerative lumbar instability

Neurosurgery. 2007 Apr;60(4 Suppl 2):203-12; discussion 212-3. doi: 10.1227/01.NEU.0000255388.03088.B7.

Abstract

Objective: Percutaneous spinal instrumentation techniques may be helpful to reduce approach-related morbidity inherent to conventional open surgery. This article reports technique, clinical outcomes, and fusion rates of percutaneous transforaminal lumbar interbody fixation (pTLIF). Results are compared with those of mini-open transforaminal lumbar interbody fixation (oTLIF) using a muscle splitting (Wiltse) approach.

Methods: pTLIF was performed in 43 patients with single-level and 10 patients with bi- or multilevel lumbar discopathy or degenerative pseudolisthesis resulting in axial back pain and claudication, pseudoradicular, or radicular symptoms. Decompression, discectomy, and interbody cage insertion were performed through 18-mm tubular retractors followed by percutaneous pedicle screw-rod fixation. Clinical outcome was assessed by early postoperative pain scores (visual analog score) and standardized functional outcome questionnaires (American Academy of Orthopedic Surgeons lumbar spine and Roland-Morris low back pain score). Fusion rates were assessed by thin-slice computed tomographic scan at 16 months. Clinical outcome, time in the operating room, intraoperative blood loss, and postoperative access-site pain were compared with an institutional reference series of 67 oTLIF procedures.

Results: Excellent and good clinical results were obtained in 46 (87%) out of 53 patients at 16 months. The time spent in the operating room was equivalent and the blood loss reduced compared with oTLIF (P < 0.01). There was no morbidity related to instrumentation. Postoperative pain was significantly lower after pTLIF after the second postoperative day (P < 0.01). The overall clinical outcome was not different from oTLIF at 8 and 16 months.

Conclusion: pTLIF allows for safe and efficient minimally invasive treatment of single and multilevel degenerative lumbar instability with good clinical results. Further prospective studies investigating long-term functional results are required to assess the definitive merits of percutaneous instrumentation of the lumbar spine.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Cohort Studies
  • Decompression, Surgical / adverse effects
  • Decompression, Surgical / methods
  • Decompression, Surgical / statistics & numerical data
  • Diskectomy, Percutaneous / adverse effects
  • Diskectomy, Percutaneous / methods
  • Diskectomy, Percutaneous / statistics & numerical data
  • Female
  • Humans
  • Lumbar Vertebrae / surgery*
  • Male
  • Middle Aged
  • Minimally Invasive Surgical Procedures* / adverse effects
  • Minimally Invasive Surgical Procedures* / methods
  • Minimally Invasive Surgical Procedures* / statistics & numerical data
  • Pain Measurement
  • Prostheses and Implants
  • Retrospective Studies
  • Spinal Diseases / diagnostic imaging
  • Spinal Diseases / surgery*
  • Spinal Fusion* / adverse effects
  • Spinal Fusion* / methods
  • Spinal Fusion* / statistics & numerical data
  • Surveys and Questionnaires
  • Tomography, X-Ray Computed
  • Treatment Outcome