Do 1-year outcomes predict 2-year outcomes for adult deformity surgery?

Spine J. 2009 Apr;9(4):317-22. doi: 10.1016/j.spinee.2008.06.450. Epub 2008 Sep 6.

Abstract

Background context: Health-related quality-of-life (HRQOL) measures are being used more frequently in the evaluation of the adult deformity patient. This is due in part to the validation of the deformity-specific Scolios Research Society-22 (SRS-22). Hence, relationships between HRQOL outcomes and traditional measures of success such as deformity correction, fusion healing, and complications are being established.

Purpose: To examine the pattern of HRQOL outcome responses after adult deformity surgery.

Study design: Analysis of prospective multicenter cohort.

Patient sample: Two hundred and eighty-three adult deformity patients with preoperative, 1-, and 2-year postoperative outcome measures.

Outcome measures: SRS-22, Short Form-12 (SF-12), Oswestry Disability Index (ODI), and back and leg pain numeric rating scale scores.

Methods: Preoperative versus postoperative health status measures were evaluated by matched-pairs sample t test statistics and post hoc analysis of variance (ANOVA) findings.

Results: SRS-22 improved from a mean 3.03 points at baseline to 3.21 points at 6 months, 3.71 points at 1 year, and 3.70 points at 2 years post-op. Mean ODI score was 37.0 points pre-op and improved to 27.0 points at 6 months, and 22.8 points at 1 and 2 years post-op. Mean SF-12 physical component score was 33.7 points at baseline, improving to 36.9 points at 6 months, 40.6 points at 1 year, and 40.5 points at 2 years post-op. Paired samples analysis comparing 6-month and 1-year post-op scores showed deterioration for numeric rating scale leg pain (p=0.05). There was a trend for improvement in SF-12 physical component score (p=0.06). Significant improvement between 6 months and 1 year post-op was noted for ODI (p=0.02) and SRS total score (p<0.0001). Comparison of 1- versus 2-year postoperative scores revealed no statistically significant differences for any of the HRQOL parameters.

Conclusions: This study supports the application of HRQOL measures, including the deformity-specific SRS-22, as a valuable tool in the assessment of adult deformity patients. Change in outcome score stabilized after the 1-year postoperative interval, for most patients.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't
  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Disability Evaluation
  • Female
  • Health Status*
  • Humans
  • Male
  • Middle Aged
  • Pain, Postoperative / physiopathology*
  • Predictive Value of Tests
  • Prospective Studies
  • Quality of Life
  • Reproducibility of Results
  • Scoliosis / physiopathology*
  • Scoliosis / surgery*
  • Spinal Fusion
  • Surveys and Questionnaires / standards*
  • Young Adult