Stem cells in bone grafting: Trinity allograft with stem cells and collagen/beta-tricalcium phosphate with concentrated bone marrow aspirate

Foot Ankle Clin. 2010 Dec;15(4):611-9. doi: 10.1016/j.fcl.2010.09.003.

Abstract

The orthopedic foot and ankle surgeon needs bone grafts in the clinical situation of fracture healing and in bone-fusion procedures. This article briefly outlines thought processes and techniques for 2 recent options for the surgeon. The Trinity product is a unique combination of allograft bone and allograft stem cells. The beta-tricalcium phosphate and collagen materials provide an excellent scaffold for bone growth; when combined with concentrated bone marrow aspirate, they also offer osteoconductive and osteoinductive as well as osteogenerative sources for new bone formation.

Publication types

  • Review

MeSH terms

  • Ankle / surgery*
  • Biocompatible Materials / therapeutic use*
  • Bone Substitutes
  • Bone Transplantation / methods*
  • Calcium Phosphates / therapeutic use*
  • Foot / surgery*
  • Humans
  • Mesenchymal Stem Cell Transplantation*
  • Transplantation, Homologous

Substances

  • Biocompatible Materials
  • Bone Substitutes
  • Calcium Phosphates
  • beta-tricalcium phosphate