Outcome of lumbar spinal fusion surgery in obese patients: a systematic review and meta-analysis

Bone Joint J. 2015 Oct;97-B(10):1395-404. doi: 10.1302/0301-620X.97B10.35724.

Abstract

The aim of this study was to determine whether obesity affects pain, surgical and functional outcomes following lumbar spinal fusion for low back pain (LBP). A systematic literature review and meta-analysis was made of those studies that compared the outcome of lumbar spinal fusion for LBP in obese and non-obese patients. A total of 17 studies were included in the meta-analysis. There was no difference in the pain and functional outcomes. Lumbar spinal fusion in the obese patient resulted in a statistically significantly greater intra-operative blood loss (weighted mean difference: 54.04 ml; 95% confidence interval (CI) 15.08 to 93.00; n = 112; p = 0.007) more complications (odds ratio: 1.91; 95% CI 1.68 to 2.18; n = 43858; p < 0.001) and longer duration of surgery (25.75 mins; 95% CI 15.61 to 35.90; n = 258; p < 0.001). Obese patients have greater intra-operative blood loss, more complications and longer duration of surgery but pain and functional outcome are similar to non-obese patients. Based on these results, obesity is not a contraindication to lumbar spinal fusion.

Keywords: low back pain; lumbar spinal fusion; meta-analysis.; obesity; systematic review.

Publication types

  • Comparative Study
  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Blood Loss, Surgical / statistics & numerical data
  • Humans
  • Length of Stay
  • Low Back Pain / surgery*
  • Lumbar Vertebrae / surgery*
  • Obesity / complications*
  • Operative Time
  • Pain, Postoperative
  • Postoperative Complications
  • Spinal Fusion*
  • Treatment Outcome