Local recurrences in giant cell tumour of bone. Long-term follow up of 31 cases

Int Orthop. 1996;20(3):172-6. doi: 10.1007/s002640050057.

Abstract

We studied the value of histopathological grading in determining the prognosis of giant cell tumour (osteoclastoma) and the rate of local and distant recurrences in a consecutive series of 31 patients. We found that grading had no prognostic value. Eighteen patients were treated by intralesional curettage and 13 by wide excision. Ten patients (56%), who were all treated by curettage, had local recurrences, but none of the tumours with wide excision recurred (p < 0.05). Five (16%) had local recurrences as well as distant metastases, usually to the lungs. The recurrences developed later than an average of 12 years after primary treatment in 3 patients. Wide excision and life-long follow up should be considered in the management of these tumours.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bone Neoplasms / classification
  • Bone Neoplasms / pathology*
  • Bone Neoplasms / surgery
  • Debridement
  • Female
  • Follow-Up Studies
  • Giant Cell Tumor of Bone / classification
  • Giant Cell Tumor of Bone / pathology*
  • Giant Cell Tumor of Bone / surgery
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Neoplasm Recurrence, Local
  • Prognosis
  • Surgical Procedures, Operative / methods