GNAS is a complex imprinted gene that uses multiple promoters to generate several gene
products, including the G protein α-subunit (G s α) that couples seven-transmembrane …

The Y-box-binding protein, YB-1, is a member of the DNA-binding protein family. It binds to
the Y-box, an inverted CCAAT box, in the promoter region of the human multidrug resistance …

Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The
use of combination chemotherapy and surgery enables long-term survival in approximately …

G s α is a ubiquitously expressed G protein α‐subunit that couples receptors to adenylyl
cyclase. Mice with chondrocyte‐specific ablation of the G s α gene had severe epiphyseal and …

The G-protein α-subunit G s α is required for the intracellular cAMP responses to hormones
and other agonists. G s α is known to mediate the cAMP response to parathyroid hormone …

This study addresses the immunohistochemical expression of the E‐cadherin and catenin
families and mutations of the β‐catenin gene detected by PCR–SSCP in synovial sarcoma. …

p53 mutation is one of the major results of ultraviolet (UV) radiation. UV photoproducts of
cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone (6–4) photoproducts (64PPs…

The hepatocyte growth factor (HGF)/c-MET signaling system plays an important role in the
carcinogenesis of various organs. We investigated the expression of HGF and its receptor c-…

Purpose: Growth factors, particularly insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR)
in some nonendocrine and a few endocrine tumors, are thought important in recurrence…

Background Congenital pseudoarthrosis of the tibia (CPT) is one of the most difficult conditions
to treat. Methods Five girls and 3 boys with CPT were treated by vascularized fibular …