User profiles for Benjamin C. Reeves
Benjamin C. ReevesYale University Verified email at yale.edu Cited by 1317 |
Glymphatic system impairment in Alzheimer's disease and idiopathic normal pressure hydrocephalus
Approximately 10% of dementia patients have idiopathic normal pressure hydrocephalus (iNPH),
an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and …
an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and …
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Hydrocephalus, characterized by cerebral ventricular dilatation, is routinely attributed to
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
primary defects in cerebrospinal fluid (CSF) homeostasis. This fosters CSF shunting as the …
Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets
Hydrocephalus is the most common neurosurgical disorder worldwide and is characterized
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …
by enlargement of the cerebrospinal fluid (CSF)-filled brain ventricles resulting from failed …
The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus
The choroid plexus (ChP) is the blood-cerebrospinal fluid (CSF) barrier and the primary
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks drug …
source of CSF. Acquired hydrocephalus, caused by brain infection or hemorrhage, lacks drug …
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus
…, BC Reeves, JK Karimy, A Marlier, C Castaldi… - Nature medicine, 2020 - nature.com
Congenital hydrocephalus (CH), characterized by enlarged brain ventricles, is considered a
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …
disease of excessive cerebrospinal fluid (CSF) accumulation and thereby treated with …
DIAPH1 variants in non–east asian patients with sporadic moyamoya disease
Importance Moyamoya disease (MMD), a progressive vasculopathy leading to narrowing and
ultimate occlusion of the intracranial internal carotid arteries, is a cause of childhood stroke…
ultimate occlusion of the intracranial internal carotid arteries, is a cause of childhood stroke…
Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury
JK Karimy, BC Reeves, KT Kahle - Expert opinion on therapeutic …, 2020 - Taylor & Francis
Recent data have implicated inflammation of the cerebrospinal fluid spaces after
subarachnoid, intraventricular, and intracerebral hemorrhage to be a critical driver of multiple …
subarachnoid, intraventricular, and intracerebral hemorrhage to be a critical driver of multiple …
Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations
…, BC Reeves, J Zhang, C Nelson-Williams… - Nature …, 2023 - nature.com
To elucidate the pathogenesis of vein of Galen malformations (VOGMs), the most common
and most severe of congenital brain arteriovenous malformations, we performed an …
and most severe of congenital brain arteriovenous malformations, we performed an …
PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets
The lack of effective treatments for autism spectrum disorder (ASD) and congenital
hydrocephalus (CH) reflects the limited understanding of the biology underlying these common …
hydrocephalus (CH) reflects the limited understanding of the biology underlying these common …
A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus
Hydrocephalus, characterized by cerebral ventriculomegaly, is the most common disorder
requiring brain surgery in children. Recent studies have implicated SMARCC1, a component …
requiring brain surgery in children. Recent studies have implicated SMARCC1, a component …