Background: Despite the use of modern instruments in total knee arthroplasty, component
malalignment remains a problem. Whether a computer-assisted implantation technique can …

Research regarding the potency and potential of the fracture hematoma has begun to
receive increasing attention. However, currently there is a paucity of relevant literature on the …

Background: The present study was designed to clarify which underlying indications can be
currently considered the main reasons for failure after total knee arthroplasty as a function of …

The biological bone healing depends on the presence of osteochondral progenitors and
their ability for proliferation. Isolated periosteal cells were seeded into biodegradable PGLA …

Bone healing commences with an inflammatory reaction which initiates the regenerative
healing process leading in the end to reconstitution of bone. An unbalanced immune reaction …

Progenitor cells such as mesenchymal stem cells (MSCs) have elicited great hopes for
therapeutic augmentation of physiological regeneration processes, eg, for bone fracture healing. …

A retrospective clinical–radiological study to evaluate the long-term outcome after artificial
disc replacement was performed. The objective is to investigate long-term results after …

Background An effective immune system, especially during the inflammatory phase, putatively
influences the quality and likelihood of bone healing. If and how this is reflected within the …

Background Bone fracture initiates a series of cellular and molecular events including the
expression of hypoxia-inducible factor (HIF)-1. HIF-1 is known to facilitate recruitment and …

Study Design. Clinical and radiologic study evaluating the outcome after nucleotomy with
dynamic stabilization compared with nucleotomy alone. Objectives. To investigate the effect of …