The impact of intraoperative local ketorolac on opioid use in the management of postoperative pain in thoracolumbar spinal fusions: a retrospective cohort study

E Lytle, C Claus, E Yoon, D Tong… - International Journal of …, 2020 - ijssurgery.com
ABSTRACT Background: The United States is facing an opioid addiction epidemic with>
63,600 deaths from drug overdoses in 2016 alone. Ketorolac is a nonsteroidal anti …

The effect of ketorolac on posterior thoracolumbar spinal fusions: a prospective double-blinded randomised placebo-controlled trial protocol

CF Claus, E Lytle, D Tong, D Sigler, D Lago… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Ketorolac has been shown to provide quality postoperative pain control and
decrease opioid requirement with minimal side effects following spinal surgery. However …

Intravenous Ketorolac Substantially Reduces Opioid Use and Length of Stay After Lumbar Fusion: A Randomized Controlled Trial

S Iyer, ME Steinhaus, GS Kazarian, EM Zgonis… - 2024 - journals.lww.com
Study Design. A randomized, double-blinded, placebo-controlled trial. Objective. To
examine the effect of intravenous ketorolac (IV-K) on hospital opioid use compared with IV …

2017 Research Grant: Intravenous ketorolac substantially reduces opioid use following lumbar spinal fusion: early results of a randomized, double-blinded, placebo …

S Iyer, EM Zgonis, ME Steinhaus, JJ Varghese, D Stein… - The Spine Journal, 2019 - Elsevier
BACKGROUND CONTEXT Lumbar spine fusions are rated among the most painful surgical
procedures. Adequately controlling postoperative pain while minimizing opioid use is an …

303. Intravenous ketorolac substantially reduces opioid use following lumbar spinal fusion: early results of a randomized, double-blinded, placebo controlled trial

S Iyer, EM Zgonis, ME Steinhaus, JJ Varghese, D Stein… - The Spine Journal, 2019 - Elsevier
BACKGROUND CONTEXT Lumbar spine fusions are rated amongst the most painful
surgical procedures. Adequately controlling post-operative pain while minimizing opioid use …

Ketorolac use for postoperative pain management following lumbar decompression surgery: a prospective, randomized, double-blinded, placebo-controlled trial

EH Cassinelli, CL Dean, RM Garcia, CG Furey… - 2008 - journals.lww.com
Study Design. Prospective randomized double-blind placebo-controlled study. Objective.
The objective of this study was to assess the efficacy of Ketorolac in reducing postoperative …

Intraoperative ketorolac dose of 15 mg versus the standard 30 mg on early postoperative pain after spine surgery: a randomized, blinded, non-inferiority trial

KM Duttchen, A Lo, A Walker, D McLuckie… - Journal of clinical …, 2017 - Elsevier
Study objective The primary aim of this study is to show the non-inferiority of 15 mg
intraoperative dose of ketorolac as compared to the standard 30 mg ketorolac by looking at …

Dose-response of ketorolac as an adjunct to patient-controlled analgesia morphine in patients after spinal fusion surgery

SS Reuben, NR Connelly, S Lurie, M Klatt… - Anesthesia & …, 1998 - journals.lww.com
This randomized, blind study was designed to determine the appropriate dose of ketorolac
(a drug used as a supplement to opioids) to administer to patients who have undergone …

The effect of ketorolac on posterior minimally invasive transforaminal lumbar interbody fusion: an interim analysis from a randomized, double-blinded, placebo …

CF Claus, E Lytle, M Lawless, D Tong, D Sigler… - The Spine Journal, 2022 - Elsevier
BACKGROUND CONTEXT Postoperative pain control following posterior lumbar fusion
continues to be challenging and often requires high doses of opioids for pain relief. The use …

The Impact of Ketorolac Utilization on Outcomes for Lumbar Spine Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

AN Baumann, A Fiorentino, K Sidloski, J Fiechter… - World Neurosurgery, 2024 - Elsevier
Introduction Ketorolac is one of the most potent non-steroidal anti-inflammatory drugs
(NSAIDs) commonly used in spine surgery. The purpose of this study is to examine the …