User profiles for GEORGE M. GHOBRIAL

George Ghobrial

Thomas Jefferson University Hospital
Verified email at jefferson.edu
Cited by 2795

Intraoperative vancomycin use in spinal surgery: single institution experience and microbial trends

GM Ghobrial, V Thakkar, E Andrews, M Lang, A Chitale… - Spine, 2014 - journals.lww.com
Study Design. Retrospective case series. Objective. To demonstrate the microbial trends of
spinal surgical site infections in patients who had previously received crystallized …

Complications from the use of intrawound vancomycin in lumbar spinal surgery: a systematic review

GM Ghobrial, DW Cadotte, K Williams, MG Fehlings… - Neurosurgical …, 2015 - thejns.org
OBJECT The use of intrawound vancomycin is rapidly being adopted for the prevention of
surgical site infection (SSI) in spinal surgery. At operative closure, the placement of …

Human neural stem cell transplantation in chronic cervical spinal cord injury: functional outcomes at 12 months in a phase II clinical trial

GM Ghobrial, KD Anderson, M Dididze… - …, 2017 - journals.lww.com
METHODS Institutional review board (IRB) approval was obtained. The Quorum IRB
evaluated and managed all participating centers in a previous Phase I/II study of HuCNS-SC®(…

Operative and nonoperative adverse events in the management of traumatic fractures of the thoracolumbar spine: a systematic review

GGM Ghobrial, CM MauluCCi, M Maltenfort… - Neurosurgical …, 2014 - thejns.org
Object Thoracolumbar spine injuries are commonly encountered in patients with trauma,
accounting for almost 90% of all spinal fractures. Thoracolumbar burst fractures comprise a …

Prophylactic vertebral cement augmentation at the uppermost instrumented vertebra and rostral adjacent vertebra for the prevention of proximal junctional kyphosis …

GM Ghobrial, DG Eichberg, JPG Kolcun, K Madhavan… - The spine journal, 2017 - Elsevier
Background Context Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF)
are common problems after long-segment (>5 levels) thoracolumbar instrumented fusions …

ASA grade and Charlson Comorbidity Index of spinal surgery patients: correlation with complications and societal costs

…, C Vernick, PG Campbell, S Yadla, GM Ghobrial… - The Spine Journal, 2014 - Elsevier
Background context The Charlson Comorbidity Index (CCI) and the American Society of
Anesthesiologists (ASA) Physical Status Classification System (ASA grade) are useful for …

Dural arteriovenous fistulas: a review of the literature and a presentation of a single institution's experience

GM Ghobrial, E Marchan, AK Nair, AS Dumont… - World neurosurgery, 2013 - Elsevier
Objective Dural arteriovenous fistulas (DAVFs) are arteriovenous shunts from a dural arterial
supply to a dural venous channel, typically supplied by pachymeningeal arteries and …

Biology of cerebral arteriovenous malformations with a focus on inflammation

…, AS Dumont, GM Ghobrial… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebral arteriovenous malformations (AVMs) entail a significant risk of intracerebral
hemorrhage owing to the direct shunting of arterial blood into the venous vasculature without the …

Iatrogenic neurologic deficit after lumbar spine surgery: a review

GM Ghobrial, KA Williams Jr, P Arnold… - Clinical Neurology and …, 2015 - Elsevier
Iatrogenic neurologic deficits after lumbar spine surgery are rare complications, but important
to recognize and manage. Complications such as radiculopathy, spinal cord compression, …

Timing in the surgical evacuation of spinal epidural abscesses

GM Ghobrial, S Beygi, MJ Viereck, CM Maulucci… - Neurosurgical …, 2014 - thejns.org
Object One often overlooked aspect of spinal epidural abscesses (SEAs) is the timing of
surgical management. Limited evidence is available correlating earlier intervention with …