The authors analyze the nation‐state as a worldwide institution constructed by worldwide
cultural and associational processes, developing four main topics: (1) properties of nation‐…

We analyze the growth of international non-governmental organizations between 1875 and
1973 using a data set on almost 6,000 organizations. Although these organizations are …

DEPOSITS of β-amyloid are apparent in ageing and Alzheimer's disease 1 , but the role of
this peptide in neurodegeneration is unclear 2 . The free-radical theory of ageing may also …

This book illuminates the central role played by international nongovernmental organizations
(INGOs) in the emergence and development of a comprehensive world polity. The …

Background The Loeys–Dietz syndrome is a recently described autosomal dominant aortic-aneurysm
syndrome with widespread systemic involvement. The disease is characterized by …

Elucidating the signalling mechanisms by which obesity leads to impaired insulin action is
critical in the development of therapeutic strategies for the treatment of diabetes 1 . Recently, …

Numerous studies have established a causal link between aberrant mammalian target of
rapamycin (mTOR) activation and tumorigenesis, indicating that mTOR inhibition may have …

Hydrogen storage is widely recognized as a critical enabling technology for the successful
commercialization and market acceptance of hydrogen powered vehicles. Storing sufficient …

The mammalian Target of Rapamycin (mTOR) protein is a serine-threonine kinase that
regulates cell-cycle progression and growth by sensing changes in energy status. We …

The murine Pten prostate cancer model described in this study recapitulates the disease
progression seen in humans: initiation of prostate cancer with prostatic intraepithelial neoplasia …