Melanoma brain metastasis (MBM) frequently occurs in patients with advanced melanoma;
yet, our understanding of the underlying salient biology is rudimentary. Here, we performed …

Background Meningiomas are the most common primary intracranial tumor in adults.
Clinical care is currently guided by the World Health Organization (WHO) grade assigned to …

Interactions between tumor cells and cancer-associated fibroblasts (CAFs) in the tumor
microenvironment significantly influence cancer growth and metastasis. Transforming growth …

Seeds of cabbage, lettuce, millet, radish, turnip, and wheat were treated with solutions
containing Be, Ni, Tl, or V, and subsequent effects on seed germination and radicle elongation …

Immunotherapy has emerged as a promising approach to treat cancer, however, its efficacy
in highly malignant brain-tumors, glioblastomas (GBM), is limited. Here, we generate distinct …

Calf diarrhea is one of the most concerning challenges facing both the dairy and beef cattle
industry. Maintaining healthy gut microbiota is essential for preventing gastrointestinal …

Background There is growing concern that the quality of inpatient care may differ on
weekends versus weekdays. We assessed the “weekend effect” in common urgent general …

Background Programmed death ligand 1 (PD-L1) contributes to tumor immunosuppression
and is upregulated in aggressive meningiomas. We performed a phase II study of nivolumab, …

The emergence of infections caused by antimicrobial resistant microorganisms (ARMs) is
currently one of the most important challenges to public health and medicine. Though …

Alcohol (EtOH) intoxication is a risk factor for increased morbidity and mortality with traumatic
injuries, in part through inhibition of bone fracture healing. Animal models have shown that …