User profiles for Peter Shen
 | Peter ShenUniversity of Utah Verified email at biochem.utah.edu Cited by 2169 |
[PDF][PDF] The structure of the polycystic kidney disease channel PKD2 in lipid nanodiscs
The Polycystic Kidney Disease 2 (Pkd2) gene is mutated in autosomal dominant polycystic
kidney disease (ADPKD), one of the most common human monogenic disorders. Here, we …
kidney disease (ADPKD), one of the most common human monogenic disorders. Here, we …
Structure of the Cdc48 segregase in the act of unfolding an authentic substrate
The cellular machine Cdc48 functions in multiple biological pathways by segregating its
protein substrates from a variety of stable environments such as organelles or multi-subunit …
protein substrates from a variety of stable environments such as organelles or multi-subunit …
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains
In Eukarya, stalled translation induces 40S dissociation and recruitment of the ribosome
quality control complex (RQC) to the 60S subunit, which mediates nascent chain degradation. …
quality control complex (RQC) to the 60S subunit, which mediates nascent chain degradation. …
Influence of age and gender on cardiac output-V˙o 2 relationships during submaximal cycle ergometry
DN Proctor, KC Beck, PH Shen… - Journal of applied …, 1998 - journals.physiology.org
Proctor, David N., Kenneth C. Beck, Peter H. Shen, Tamara J. Eickhoff, John R. Halliwill, and
Michael J. Joyner. Influence of age and gender on cardiac output-Vo 2 relationships during …
Michael J. Joyner. Influence of age and gender on cardiac output-Vo 2 relationships during …
[HTML][HTML] A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress
The conserved transcriptional regulator heat shock factor 1 (Hsf1) is a key sensor of
proteotoxic and other stress in the eukaryotic cytosol. We surveyed Hsf1 activity in a genome-wide …
proteotoxic and other stress in the eukaryotic cytosol. We surveyed Hsf1 activity in a genome-wide …
Dicer uses distinct modules for recognizing dsRNA termini
Invertebrates rely on Dicer to cleave viral double-stranded RNA (dsRNA), and Drosophila
Dicer-2 distinguishes dsRNA substrates by their termini. Blunt termini promote processive …
Dicer-2 distinguishes dsRNA substrates by their termini. Blunt termini promote processive …
Reduced leg blood flow during dynamic exercise in older endurance-trained men
DN Proctor, PH Shen, NM Dietz… - Journal of applied …, 1998 - journals.physiology.org
It is currently unclear whether aging alters the perfusion of active muscles during large-muscle
dynamic exercise in humans. To study this issue, direct measurements of leg blood flow (…
dynamic exercise in humans. To study this issue, direct measurements of leg blood flow (…
[PDF][PDF] The P/E ratio and stock market performance
P Shen - Economic review-Federal reserve bank of Kansas city, 2000 - Citeseer
The US stock market enters the new mil-lennium with five consecutive years of exceptional
gains. The S&P 500 index has gained more than 18 percent each of these five years and its …
gains. The S&P 500 index has gained more than 18 percent each of these five years and its …
[HTML][HTML] Active conformation of the p97-p47 unfoldase complex
The p97 AAA+ATPase is an essential and abundant regulator of protein homeostasis that
plays a central role in unfolding ubiquitylated substrates. Here we report two cryo-EM …
plays a central role in unfolding ubiquitylated substrates. Here we report two cryo-EM …
Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
10.7554/eLife.24487.001 Many important cellular membrane fission reactions are driven by
ESCRT pathways, which culminate in disassembly of ESCRT-III polymers by the AAA …
ESCRT pathways, which culminate in disassembly of ESCRT-III polymers by the AAA …
