User profiles for Sandhya Sundaram

Sandhya - Sundaram

Professor and Head , Pathology and Senior Consultant, Sri Ramachandra Medical College …
Verified email at sriramachandra.edu.in
Cited by 773

SLC7A11/xCT is a target of miR-5096 and its restoration partially rescues miR-5096-mediated ferroptosis and anti-tumor effects in human breast cancer cells

P Yadav, P Sharma, S Sundaram, G Venkatraman… - Cancer letters, 2021 - Elsevier
Breast cancer cells evade cell death by overexpressing SLC7A11, which functions by
transporting cystine into cells in exchange for intracellular glutamate facilitating glutathione …

Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells

C Kishore, S Sundaram, D Karunagaran - Chemico-Biological Interactions, 2019 - Elsevier
Tumor recurrence and metastasis decrease the survival rate of colorectal cancer (CRC)
patients. Menadione reduces the numbers and incidences of 1,2-dimethylhydrazine induced …

Deregulated metabolic pathways in ovarian cancer: cause and consequence

R Murali, V Balasubramaniam, S Srinivas, S Sundaram… - Metabolites, 2023 - mdpi.com
Ovarian cancers are tumors that originate from the different cells of the ovary and account
for almost 4% of all the cancers in women globally. More than 30 types of tumors have been …

Zinc transporter LIV1: A promising cell surface target for triple negative breast cancer

…, I Ezhil, Z Afnaan, J John, S Sundaram… - Journal of Cellular …, 2022 - Wiley Online Library
Breast cancer is one of the leading causes contributing to the global cancer burden. The triple
negative breast cancer (TNBC) molecular subtype accounts for the most aggressive type. …

[HTML][HTML] Reductive stress promotes protein aggregation and impairs neurogenesis

KKS Narasimhan, A Devarajan, G Karan, S Sundaram… - Redox biology, 2020 - Elsevier
Redox homeostasis regulates key cellular signaling in both physiology and pathology.
While perturbations result in shifting the redox homeostasis towards oxidative stress are well …

Coronary atherosclerosis in sudden cardiac death: An autopsy study

ML Sudha, S Sundaram… - Indian Journal of …, 2009 - journals.lww.com
Background: The incidence of ischemic heart disease (IHD) has markedly increased in India
over the past few years. Considering the variations in racial, dietary and lifestyle patterns in …

HMGB3 inhibition by miR-142-3p/sh-RNA modulates autophagy and induces apoptosis via ROS accumulation and mitochondrial dysfunction and reduces the …

P Sharma, P Yadav, S Sundaram, G Venkatraman… - Life Sciences, 2022 - Elsevier
Aims High mobility group box (HMGB) family proteins, HMGB1, HMGB2, HMGB3, and HMGB4
are oncogenic. The oncogenic nature of HMGB1 is characterized by its association with …

Biomechanical evaluation of a pre-contoured clavicle plate

…, RJ Markert, CG Anderson, SS Sundaram… - Journal of shoulder and …, 2008 - Elsevier
Recent attention has been focused on the operative treatment of mid-shaft fractures of the
clavicle. This study compares the in-vitro biomechanical properties of a pre-formed titanium …

Navigating Tumour Microenvironment and Wnt Signalling Crosstalk: Implications for Advanced Cancer Therapeutics

…, TD Hubert, R Rajaraman, F Arfuso, S Sundaram… - Cancers, 2023 - mdpi.com
Simple Summary The tumour microenvironment comprises cellular components and the
extracellular matrix, which surround the core of cancer cells and play a vital role in their …

[HTML][HTML] Role of FGFR3 in urothelial carcinoma

M Akanksha, S Sandhya - Iranian Journal of Pathology, 2019 - ncbi.nlm.nih.gov
Results: IHC expression of FGFR3 in high grade (HG) invasive urothelial carcinoma was
positive in 18% cases, 66.7% of HG non-invasive urothelial and 82.6% of low grade (LG) …