Fracture-related infection (FRI) remains a challenging complication that imposes a heavy
burden on orthopaedic trauma patients. The surgical management eradicates the local …

Aims The efficacy and safety of intrawound vancomycin for preventing surgical site infection
in primary hip and knee arthroplasty is uncertain. Methods A systematic review of the …

Antibiotic‐loaded bone cement (ALBC) is broadly used to treat orthopaedic infections based
on the rationale that high‐dose local delivery is essential to eradicate biofilm‐associated …

In this study, we developed a poly (β-amino ester)(PBAE) hydrogel for the double release of
vancomycin (VAN) and total flavonoids of Rhizoma Drynariae (TFRD). VAN was covalently …

Background: Surgical site infections (SSIs) after anterior cruciate ligament (ACL)
reconstruction procedures are an unfortunate complication. Soaking grafts in vancomycin …

Advanced porous synthetic scaffolds are particularly suitable for regeneration of damaged
tissues, but there is the risk of infections due to the colonization of microorganisms, forming …

It is important to consider mechanical, biological, and antibacterial properties of scaffolds
when used for tissue engineering applications. This study presents a method to create …

Acute bacterial skin and skin structure infections (ABSSSIs) confer a substantial burden on
the healthcare system. Local antibiotic delivery systems can provide controlled drug release …

Reconstruction of the diabetic Charcot foot can be a challenge even for experienced
surgeons. In addition to peripheral neuropathy and diabetes mellitus (DM), patients often …

Background: Vancomycin is frequently applied locally to the operative site during foot and
ankle procedures to help prevent infection. Although the efficacy of locally applied …