The authors provide a comprehensive summary of all randomized, controlled trials (n= 76)
involving the clinical administration of liposomal bupivacaine (Exparel; Pacira …

Abstract Purpose of Review Multimodal pain management is the most effective way to treat
postsurgical pain. However, the use of opioids for acute pain management has unfortunately …

BACKGROUND CONTEXT Spine surgery with posterior approaches may involve extensive
manipulation of native structures, resulting in significant postoperative pain. Liposomal …

Adequate analgesia is known to improve outcomes after spine surgery. Despite recent
attention highlighting the negative effects of narcotics and their addiction potential, opioids …

Background Most severe pain occurs within the first 72 hours after an operation, and current
local anesthetics have a limited duration of action. HTX-011 is a dual-acting, local anesthetic …

Background The opioid epidemic is at epic proportions currently in the United States.
Exposure to opioids for surgery and subsequent postoperative pain management is a known …

In recent years, physicians and institutions have come to recognize the increasing opioid
epidemic in the United States, thus prompting a dramatic shift in opioid prescribing patterns …

Study Design: A retrospective cohort review. Objectives: The objective of this study was to
investigate the efficacy of liposomal bupivacaine (LB) in patients undergoing lumbar spinal …

Introduction Spine surgery is one of the most common types of surgeries performed in the
United States; however, managing postoperative pain following spine surgery has proven to …

Patients undergoing spinal surgery are at high risk of acute and persistent postoperative
pain. Therefore, adequate pain relief is crucial. This systematic review aimed to provide …