Glioblastoma is the most common and most aggressive primary brain tumour. Standard of
care consists of surgical resection followed by radiotherapy and concomitant and …

Prostate cancer resistance to castration occurs because tumours acquire the metabolic
capability of converting precursor steroids to 5α-dihydrotestosterone (DHT), promoting signalling …

Purpose Standard therapies for localized inoperable intrahepatic cholangiocarcinoma (IHCC)
are ineffective. Advances in radiotherapy (RT) techniques and image guidance have …

Purpose This guideline provides evidence-based recommendations addressing the
indications for radiation therapy (RT), sequencing of local therapies, and appropriate dose and …

Purpose We compared proton beam therapy (PBT) with intensity modulated radiation therapy
(IMRT) for pediatric craniopharyngioma in terms of disease control, cyst dynamics, and …

Importance Neurofibromatosis type 1 (NF1) is a complex genetic disorder that is associated
with not only neurofibromas, but also an increased susceptibility to other neoplasms. …

PURPOSE: Valproic acid (VA) is an antiepileptic drug (AED) and histone deacetylase (HDAC)
inhibitor taken by patients with glioblastoma (GB) to manage seizures, and it can …

We hypothesized that myocardial perfusion imaging (MPI) would fail to identify all vascular
zones with the potential for myocardial ischemia in patients with multivessel coronary disease …

The isotopic composition of methane is of longstanding geochemical interest, with important
implications for understanding petroleum systems, atmospheric greenhouse gas …

OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive group
of soft tissue sarcomas that can arise sporadically, in the context of neurofibromatosis Type 1 …