Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall;
their hemorrhage commonly results in severe neurologic impairment and death. We report a …

The pathogenesis of intracranial aneurysm (IA) formation and rupture is complex, with
significant contribution from genetic factors. We previously reported genome-wide association …

Objective Despite surgical, technological, medical, and anesthetic improvements, patient
outcomes following elective neurosurgical procedures can be associated with high morbidity. …

DESPITE ADVANCES IN the treatment of intracranial aneurysms (IA) in recent years, the
overall outcome of patients with aneurysmal subarachnoid hemorrhage has shown only …

Spinal Cord Injury (SCI) is a major challenge in Neurotrauma research. Complex pathophysiological
processes take place immediately after the injury and later on as the chronic injury …

OBJECTIVE Enhanced recovery after surgery (ERAS) protocols address pre-, peri-, and
postoperative factors of a patient’s surgical journey. The authors sought to assess the effects of a …

The identification of pathways that underlie common disease has been greatly impacted by
the study of rare families that segregate single genes with large effect. Intracranial aneurysm …

… accomplished by using sodium dodecyl sulfate and proteinase K, followed by phenol-chloroform
extraction and … Bulent Guclu, MD and Ali K. Ozturk, BA contributed equally to this work. …

Background and Purpose— Both environmental and genetic factors contribute to the formation,
growth, and rupture of intracranial aneurysms (IAs). To search for IA susceptibility genes, …

Background and Purpose— Mutations in CCM2 (MGC4607 or malcavernin) cause familial
cerebral cavernous malformation (CCM), an autosomal dominant neurovascular disease. …