Non-white race and concomitant orthopedic conditions are risk factors for failure to achieve clinically relevant improvement after total knee arthroplasty

SN Baxter, JC Brennan, AH Johnson, L Chapa… - The Journal of …, 2024 - Elsevier
Background Data from the American Joint Replacement Registry demonstrate that 1-year
minimal clinically important difference (MCID) achievement rates after total knee arthroplasty (…

Managing an epidemic within a pandemic: orthopedic opioid prescribing trends during COVID-19

JJ Turcotte, JC Brennan, AH Johnson, PJ King… - Archives of Orthopaedic …, 2024 - Springer
Materials and methods A retrospective review of 1,048,559 patient encounters from January
1, 2015 to December 31, 2022 at a single orthopedic practice was performed. Primary …

[HTML][HTML] Comparison of Postoperative Outcomes of Patients Undergoing Total Hip and Total Knee Arthroplasty Following a Diagnosis of Dementia: A TriNetX …

AH Johnson, JC Brennan, PJ King, JJ Turcotte… - Arthroplasty Today, 2024 - Elsevier
Background As life expectancy improves for patients with dementia, the demand for mobility-improving
surgeries such as total joint arthroplasty (TJA) will increase. There is little …

Addressing the Challenge of Spine Patient Triage: Development of a Simple Algorithm for Identification of Potential Surgical Candidates

JJ Turcotte, JC Brennan, AH Johnson… - JAAOS-Journal of the …, 2024 - journals.lww.com
Methods: A retrospective review of 5,886 consecutive new patients presenting to a
multidisciplinary spine clinic from March 2021 to September 2022 was conducted. The primary …

Discovery of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular …

…, KW Hinkle, RN Hunter III, JH Johnson… - Journal of medicinal …, 2008 - ACS Publications
Inhibition of the vascular endothelial growth factor (VEGF) signaling pathway has emerged as
one of the most promising new approaches for cancer therapy. We describe herein the key …

Pharmacokinetic-pharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic …

R Kumar, VB Knick, SK Rudolph, JH Johnson… - Molecular cancer …, 2007 - AACR
With the development of targeted therapeutics, especially for small-molecule inhibitors, it is
important to understand whether the observed in vivo efficacy correlates with the modulation …

Discovery and evaluation of 2-anilino-5-aryloxazoles as a novel class of VEGFR2 kinase inhibitors

…, L Wang, W Liu, RM Crosby, JH Johnson… - Journal of medicinal …, 2005 - ACS Publications
A series of derivatives of 2-anilino-5-phenyloxazole (5) has been identified as inhibitors of
VEGFR2 kinase. Herein we describe the structure−activity relationship (SAR) of this novel …

Severity Indices of Personality Problems (SIPP-118): development, factor structure, reliability, and validity.

R Verheul, H Andrea, CC Berghout… - Psychological …, 2008 - psycnet.apa.org
This article describes a series of studies involving 2,730 participants on the development
and validity testing of the Severity Indices of Personality Problems (SIPP), a self-report …

Effectiveness of different modalities of psychotherapeutic treatment for patients with cluster C personality disorders: results of a large prospective multicentre study

A Bartak, MD Spreeuwenberg, H Andrea… - Psychotherapy and …, 2009 - karger.com
Background: No previous studies have compared the effectiveness of different modalities of
psychotherapeutic treatment, as defined by different settings and durations, for patients with …

Effectiveness of outpatient, day hospital, and inpatient psychotherapeutic treatment for patients with cluster B personality disorders

A Bartak, H Andrea, MD Spreeuwenberg… - Psychotherapy and …, 2010 - karger.com
Background: For patients with cluster B personality disorders there is no consensus regarding
the optimal treatment setting. The aim of this study was to compare the effectiveness of …