The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization
…, R Pasqualini, RA Lindberg, R Kain, AL Freeman… - Oncogene, 2000 - nature.com
Eph receptor tyrosine kinases and their ephrin ligands have been implicated in embryonic
vascular development and in in vivo models of angiogenesis. Eph proteins may also regulate …
vascular development and in in vivo models of angiogenesis. Eph proteins may also regulate …
Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth
NK Noren, M Lu, AL Freeman… - Proceedings of the …, 2004 - National Acad Sciences
Receptor tyrosine kinases of the Eph family are up-regulated in different types of cancer. EphB4
and its ligand ephrin-B2 have been linked to breast cancer, but little is known about how …
and its ligand ephrin-B2 have been linked to breast cancer, but little is known about how …
Prevention of venous thromboembolism in obesity
AL Freeman, RC Pendleton… - Expert review of …, 2010 - Taylor & Francis
Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in hospitalized
patients. Where appropriate, evidence-based methods of prophylaxis are implemented …
patients. Where appropriate, evidence-based methods of prophylaxis are implemented …
Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological …
AH Zisch, C Pazzagli, AL Freeman, M Schneller… - Oncogene, 2000 - nature.com
Eph receptor tyrosine kinases play key roles in pattern formation during embryonic
development, but little is known about the mechanisms by which they elicit specific biological …
development, but little is known about the mechanisms by which they elicit specific biological …
How much do locked screws add to the fixation of “hybrid” plate constructs in osteoporotic bone?
AL Freeman, P Tornetta III, A Schmidt… - … of orthopaedic trauma, 2010 - journals.lww.com
Background: Hybrid locked plating has become a commonly used technique for treating
complex fractures and nonunions, but information is lacking to direct the specific application of …
complex fractures and nonunions, but information is lacking to direct the specific application of …
Biomechanical analysis of sacral screw strain and range of motion in long posterior spinal fixation constructs: effects of lumbosacral fixation strategies in reducing …
GD Fleischer, YJ Kim, LA Ferrara, AL Freeman… - Spine, 2012 - journals.lww.com
Study Design. A cadaveric biomechanical experiment was conducted to assess the range of
motion (ROM) and screw strain at S1 in a long instrumented spinal fusion construct to …
motion (ROM) and screw strain at S1 in a long instrumented spinal fusion construct to …
[HTML][HTML] Range of motion, sacral screw and rod strain in long posterior spinal constructs: a biomechanical comparison between S2 alar iliac screws with traditional …
…, A Field, LA Ferrara, AL Freeman… - Journal of Spine …, 2016 - ncbi.nlm.nih.gov
Background S1 screw failure and L5/S1 non-union are issues with long fusions to S1. Improved
construct stiffness and S1 screw offloading can help avoid this. S2AI screws have shown …
construct stiffness and S1 screw offloading can help avoid this. S2AI screws have shown …
Inter-laboratory variability in in vitro spinal segment flexibility testing
DJ Wheeler, AL Freeman, AM Ellingson… - Journal of …, 2011 - Elsevier
In vitro spine flexibility testing has been performed using a variety of laboratory-specific loading
apparatuses and conditions, making test results across laboratories difficult to compare. …
apparatuses and conditions, making test results across laboratories difficult to compare. …
Interbody device endplate engagement effects on motion segment biomechanics
GR Buttermann, BP Beaubien, AL Freeman, JE Stoll… - The Spine Journal, 2009 - Elsevier
BACKGROUND CONTEXT: Stand-alone nonbiologic interbody fusion devices for the lumbar
spine have been used for interbody fusion since the early 1990s. However, most devices …
spine have been used for interbody fusion since the early 1990s. However, most devices …
Randomized trial of physician alerts for thromboprophylaxis after discharge
…, JJ Akus, SM Stevens, CG Elliott, AL Freeman… - The American Journal of …, 2013 - Elsevier
BACKGROUND: Many hospitalized Medical Service patients are at risk for venous
thromboembolism in the months after discharge. We conducted a multicenter randomized controlled …
thromboembolism in the months after discharge. We conducted a multicenter randomized controlled …