Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and
is associated with tumor aggression and poor clinical outcome. The effect of high levels of c…

A technique called optical coherence tomography (OCT) has been developed for noninvasive
cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to …

Master transcription factors Oct4, Sox2, and Nanog bind enhancer elements and recruit
Mediator to activate much of the gene expression program of pluripotent embryonic stem cells (…

Amber is the collective name for a suite of programs that allow users to carry out molecular
dynamics simulations, particularly on biomolecules. None of the individual programs carries …

Chromatin regulators have become attractive targets for cancer therapy, but it is unclear
why inhibition of these ubiquitous regulators should have gene-specific effects in tumor cells. …

Objective: To demonstrate optical coherence tomography for high-resolution, noninvasive
imaging of the human retina. Optical coherence tomography is a new imaging technique …

Circulating tumor cell clusters (CTC clusters) are present in the blood of patients with cancer
but their contribution to metastasis is not well defined. Using mouse models with tagged …

Background/Purpose: To assess the potential of a new diagnostic technique called optical
coherence tomography for imaging macular disease. Optical coherence tomography is a …

Recruitment of the RNA polymerase II (Pol II) transcription initiation apparatus to promoters
by specific DNA-binding transcription factors is well recognized as a key regulatory step in …

Objective: To demonstrate a new diagnostic technique, optical coherence tomography, for
highresolution cross-sectional imaging of structures in the anterior segment of the human eye …