The aging of the global population: the changing epidemiology of disease and spinal disorders
…, T Choma, J Harrop, T Mroz, C Santaguida… - …, 2015 - journals.lww.com
The global population is currently undergoing an upward shift in its age structure due to
decreasing fertility rates and increasing life expectancy. As a result, clinicians worldwide will be …
decreasing fertility rates and increasing life expectancy. As a result, clinicians worldwide will be …
[HTML][HTML] Neural stem/progenitor cells from the adult human spinal cord are multipotent and self-renewing and differentiate after transplantation
AJ Mothe, T Zahir, C Santaguida, D Cook, CH Tator - PloS one, 2011 - journals.plos.org
Neural stem/progenitor cell (NSPC) transplantation is a promising therapy for spinal cord
injury (SCI). However, little is known about NSPC from the adult human spinal cord as a donor …
injury (SCI). However, little is known about NSPC from the adult human spinal cord as a donor …
Systemic and topical use of tranexamic acid in spinal surgery: a systematic review
Study Design Combination of narrative and systematic literature reviews. Objectives Massive
perioperative blood loss in complex spinal surgery often requires blood transfusions and …
perioperative blood loss in complex spinal surgery often requires blood transfusions and …
Laminectomy and fusion versus laminoplasty for the treatment of degenerative cervical myelopathy: results from the AOSpine North America and International …
MG Fehlings, C Santaguida, L Tetreault, P Arnold… - The spine journal, 2017 - Elsevier
Background Context It remains unclear whether cervical laminoplasty (LP) offers advantages
over cervical laminectomy and fusion (LF) in patients undergoing posterior decompression …
over cervical laminectomy and fusion (LF) in patients undergoing posterior decompression …
[HTML][HTML] Single-cell RNA sequencing reveals time-and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain
Activation of microglia in the spinal cord following peripheral nerve injury is critical for the
development of long-lasting pain hypersensitivity. However, it remains unclear whether distinct …
development of long-lasting pain hypersensitivity. However, it remains unclear whether distinct …
Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo …
…, ST Yoon, KD Kim, DR Fourney, C Santaguida… - The Lancet …, 2021 - thelancet.com
Background Degenerative cervical myelopathy represents the most common form of non-traumatic
spinal cord injury. This trial investigated whether riluzole enhances outcomes in …
spinal cord injury. This trial investigated whether riluzole enhances outcomes in …
[HTML][HTML] Continuous monitoring of surgical bimanual expertise using deep neural networks in virtual reality simulation
…, N Ledwos, AM Fazlollahi, C Santaguida… - NPJ Digital …, 2022 - nature.com
In procedural-based medicine, the technical ability can be a critical determinant of patient
outcomes. Psychomotor performance occurs in real-time, hence a continuous assessment is …
outcomes. Psychomotor performance occurs in real-time, hence a continuous assessment is …
Association between paraspinal muscle morphology, clinical symptoms, and functional status in patients with degenerative cervical myelopathy
…, M Courtemanche, CJ Sparrey, C Santaguida… - Spine, 2017 - journals.lww.com
Study Design. A cross-sectional study. Objective. The aim of this study was to assess fatty
infiltration and asymmetry of the multifidus (MF), semispinalis cervicis (SCer), semispinalis …
infiltration and asymmetry of the multifidus (MF), semispinalis cervicis (SCer), semispinalis …
Clinical and pathological outcomes after resection of intramedullary spinal cord tumors: a single-institution case series
N Samuel, L Tetreault, C Santaguida, A Nater… - Neurosurgical …, 2016 - thejns.org
OBJECTIVE The objective of this study was to identify clinically relevant predictors of
progression-free survival and functional outcomes in patients who underwent surgery for …
progression-free survival and functional outcomes in patients who underwent surgery for …
The state-of-the-art in ultrasound-guided spine interventions
HE Gueziri, C Santaguida, DL Collins - Medical Image Analysis, 2020 - Elsevier
During the last two decades, intra-operative ultrasound (iUS) imaging has been employed
for various surgical procedures of the spine, including spinal fusion and needle injections. …
for various surgical procedures of the spine, including spinal fusion and needle injections. …