The inner membrane complex (IMC) of Toxoplasma gondii is a peripheral membrane system
that is composed of flattened alveolar sacs that underlie the plasma membrane, coupled to …

Astrocytes are glial cells that interact with neuronal synapses via their distal processes,
where they remove glutamate and potassium (K + ) from the extracellular space following …

Toxoplasma gondii is an obligate intracellular parasite that invades host cells and replicates
within a unique parasitophorous vacuole. To maintain this intracellular niche, the parasite …

A role for vitamin A in host defense against Mycobacterium tuberculosis has been suggested
through epidemiological and in vitro studies; however, the mechanism is unclear. In this …

The Toxoplasma inner membrane complex (IMC) is a specialized organelle underlying the
parasite's plasma membrane that consists of flattened rectangular membrane sacs that are …

Apicomplexans facilitate host cell invasion through formation of a tight-junction interface
between parasite and host plasma membranes called the moving junction (MJ). A complex of …

Background The immune system depends on effector pathways to eliminate invading pathogens
from the host in vivo. Macrophages (MΦ) of the innate immune system are armed with …

Introduction Bladder cancer (BCa) is one of the most common and aggressive cancers. It is
the sixth most frequently occurring cancer in men and its rate of occurrence increases with …

A low plasma homocyst(e)ine concentration in premenopausal and pregnant women compared
with postmenopausal women and men suggests that steroid hormones are nongenetic …

Toxoplasma gondii uses unique secretory organelles called rhoptries to inject an array of
effector proteins into the host cytoplasm that hijack host cell functions. We have discovered a …