House dust mite (HDM) allergens are important factors in the increasing prevalence of
asthma. The lung epithelium forms a barrier that allergens must cross before they can cause …

The role of mites of the family Pyroglyphidae as the single most important source of house
dust allergens was established 20 years ago.’Since that time, evidence for sensitization of …

Epithelia from many tissues express protease-activated receptors (PARs) that play a major
role in several different physiological processes. In this study, we examined their capacity to …

In previous studies, we demonstrated that allergenic house dust mite proteases are potent
inducers of proinflammatory cytokines from the respiratory epithelium, although the precise …

Endogenous proteolytic enzymes have been shown to be potential sources of airway
inflammation inducing proinflammatory cytokine release from respiratory epithelial cells; however, …

The aim of this study was to determine the extent of ankle muscle weakness in children with
cerebral palsy (CP) and to identify potential causes. Maximal voluntary contractions of …

As noted in the Department of Homeland Security's National Response Framework,
disasters are inherently local and ultimately the responsibility of the lowest jurisdictional level …

Background: Protease-activated receptors (PARs), which are G protein–coupled receptors
that are activated after proteolytic cleavage of the amino terminus of the receptor, are likely to …

Sequence analyses have revealed the existence of homology between certain aeroallergens
and proteolytic enzymes. This homology can be expressed functionally, but its significance …

The polarization of the immune response toward a Th2 or a Th1 profile can be mediated by
dendritic cells (DCs) following antigen presentation and interaction with T cells. …