In search of the astrocytic factor (s) modulating blood–brain barrier functions in brain capillary endothelial cells in vitro

RF Haseloff, IE Blasig, HC Bauer, H Bauer - Cellular and molecular …, 2005 - Springer
The blood–brain barrier (BBB) is formed by brain capillary endothelial cells (ECs). There are
various cell types, in particular astrocytes, but also pericytes and neurons, located in close …

[HTML][HTML] The dual role of zonula occludens (ZO) proteins

…, A Lametschwandtner, HC Bauer - BioMed Research …, 2010 - hindawi.com
ZO (zonula occludens) proteins are scaffolding proteins providing the structural basis for the
assembly of multiprotein complexes at the cytoplasmic surface of intercellular junctions. In …

[HTML][HTML] “You Shall Not Pass”—tight junctions of the blood brain barrier

HC Bauer, IA Krizbai, H Bauer… - Frontiers in Neuroscience, 2014 - frontiersin.org
The structure and function of the barrier layers restricting the free diffusion of substances
between the central nervous system (brain and spinal cord) and the systemic circulation is of …

[HTML][HTML] The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history

…, MD Habgood, K Møllgård, HC Bauer - Frontiers in …, 2014 - frontiersin.org
Careful examination of relevant literature shows that many of the most cherished concepts
of the blood-brain barrier are incorrect. These include an almost mythological belief in its …

[HTML][HTML] The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch

…, IA Krizbai, F Fresser, HC Bauer, H Bauer - Journal of Biological …, 2002 - ASBMB
Tight junctions create a highly selective diffusion barrier between epithelial and endothelial
cells by preventing the free passage of molecules and ions across the paracellular pathway. …

HIV‐Tat protein induces oxidative and inflammatory pathways in brain endothelium

…, G Flora, R Garrido, B Hennig, HC Bauer… - Journal of …, 2003 - Wiley Online Library
… Cloned porcine BMEC were provided by Dr HC Bauer (Institute of Molecular Biology,
Salzburg, Austria) and cultured as described earlier (Bauer et al. 1993; McGovern et al. 1994). …

Oxidative stress and blood–brain barrier dysfunction under particular consideration of matrix metalloproteinases

…, I Krizbai, B Hennig, HC Bauer, H Bauer - Antioxidants & redox …, 2011 - liebertpub.com
Bauer and HC Bauer HC are participants of the NEUROBID consortium (EU 7 th FP). … H,
Bresgen N, Eckl PM, Farkas A, Szatmari E, Traweger A, Wejksza K, and Bauer HC. Effect of …

Glial cells and neurons induce blood-brain barrier related enzymes in cultured cerebral endothelial cells

U Tontsch, HC Bauer - Brain research, 1991 - Elsevier
… 4 Bauer, HC and Tontsch, U., Glial conditioned medium and attachment to Con A are … and
Bauer, HC, Isolation, characterization, and long-term cultivation of porcine and murine cerebral …

[HTML][HTML] Zinc protects against apoptosis of endothelial cells induced by linoleic acid and tumor necrosis factor α

…, P Ramadass, M Toborek, HC Bauer, H Bauer… - The American journal of …, 2000 - Elsevier
Background: Zinc requirements of the vascular endothelium may be increased in inflammatory
conditions, ie, atherosclerosis, in which apoptotic cell death is prevalent. Objective: We …

Hedgehog‐EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour‐initiating pancreatic cancer cells

…, K Zoidl, H Schnidar, H Hache, HC Bauer… - EMBO molecular …, 2012 - embopress.org
Inhibition of Hedgehog (HH)/GLI signalling in cancer is a promising therapeutic approach.
Interactions between HH/GLI and other oncogenic pathways affect the strength and …