Background There is presently insufficient data on small groups of patients, without focus on
time since herniation occurred and without establishing a valid method of measurement for …

Background Patients with a lumbar disc herniation (LDH) without high-grade neurological
deficit (PWN) are usually treated non-operatively. If non-operative treatment is not successful, …

The conservation of large carnivores is a formidable challenge for biodiversity conservation.
Using a data set on the past and current status of brown bears (Ursus arctos), Eurasian lynx (…

Background Doxorubicin is an important cytotoxic drug in anticancer therapy and part of most
treatment protocols for children with acute leukemias or solid tumors. However, its use is …

An important pragmatic aspect of user experience is intuitive interaction. Intuitive interaction
is defined as the extent to which a product can be used by subconsciously applying prior …

Background—The death of cardiac cells during ischemia and reperfusion is partially mediated
by apoptosis, as seen, eg, in autopsy material of patients after acute myocardial infarction. …

The human mitochondrial ClpXP protease complex (HsClpXP) has recently attracted major
attention as a target for novel anti-cancer therapies. Despite its important role in disease …

GPUs are widespread across clusters of compute nodes due to their attractive performance
for data parallel codes. However, communicating between GPUs across the cluster is …

INTRODUCTION Molecularly targeted drugs such as imatinib and crizotinib have revolutionized
the treatment of certain blood and lung cancers because of their remarkable clinical …

Acute myeloid leukemia (AML) is a clinically and molecularly heterogeneous disease with
poor outcome. Adequate model systems are required for preclinical studies to improve …