BACKGROUND CONTEXT: Cervical total disc replacement (TDR) is intended to address
radicular pain and preserve functional motion between two vertebral bodies in patients with …

… Address correspondence and reprint requests to Jack Zigler, MD, Texas Back Institute/Texas
Health Research Institute, Suite 200, 6020 W. Parker Road, Plano, TX 75093; E-mail: [email …

Study Design. Randomized controlled trial. Objective. Analyze the clinical outcomes at 5
years comparing cervical total disc replacement (TDR) with ProDisc-C (Synthes Spine USA …

Background: In patients with single-level cervical degenerative disc disease, total disc
arthroplasty can relieve radicular pain and preserve functional motion between two vertebrae. We …

Study Design. Prospective randomized clinical trial. Objective. Determine the reasons for,
and rates of, secondary surgical intervention up to 5 years at both the index and adjacent …

Object The purpose of this study was to evaluate the long-term safety and effectiveness of
the ProDisc-L total disc replacement (TDR) as part of an FDA-mandated postmarket approval …

Introduction There is increasing interest in the role of cervical total disc replacement (TDR)
as an alternative to anterior cervical discectomy and fusion (ACDF). Multiple prospective …

Background: Disc replacement arthroplasty previously has been shown to be an effective
alternative to spine fusion for the treatment of single-level lumbar degenerative disc disease. …

There is an increasing population of immunocompromised patients with HIV, IV drug abuse,
organ transplantation, and long-term steroid treatment developing spinal infections. Delayed …

Object The authors report the 5-year results for radiographically demonstrated adjacent-level
degenerative changes from a prospective multicenter study in which patients were …