User profiles for John Irwin

John J. Irwin

Associate Professor, University of California San Francisco
Verified email at cgl.ucsf.edu
Cited by 28105

Thieves, convicts and the inmate culture

J Irwin, DR Cressey - Soc. Probs., 1962 - HeinOnline
CONCLUSION Legal accusation imposes a variety of consequences, depending on the nature
of the accusation and the characteristics of the accused. Deprivations occur, even though …

[BOOK][B] The jail: Managing the underclass in American society

J Irwin - 2013 - books.google.com
Combining extensive interviews with his own experience as an inmate, John Irwin constructs
a powerful and graphic description of the big-city jail. Unlike prisons, which incarcerate …

Aspect-oriented programming

…, C Maeda, C Lopes, JM Loingtier, J Irwin - ECOOP'97—Object …, 1997 - Springer
We have found many programming problems for which neither procedural nor object-oriented
programming techniques are sufficient to clearly capture some of the important design …

[BOOK][B] The felon

J Irwin - 1987 - books.google.com
Based on in-depth interviews and two years of participant observation of felons, this book
traces the career paths of such criminal types as the thief, the hustler, and the junkie, as well as …

Prisons in turmoil

J Irwin - 1980 - ojp.gov
Prisons are separated into three types according to their social organization. The'Big House'dominated
the first half of this century after prison reforms eliminated most corporal …

ZINC− a free database of commercially available compounds for virtual screening

JJ Irwin, BK Shoichet - Journal of chemical information and …, 2005 - ACS Publications
A critical barrier to entry into structure-based virtual screening is the lack of a suitable, easy
to access database of purchasable compounds. We have therefore prepared a library of 727 …

ZINC 15–ligand discovery for everyone

T Sterling, JJ Irwin - Journal of chemical information and modeling, 2015 - ACS Publications
Many questions about the biological activity and availability of small molecules remain
inaccessible to investigators who could most benefit from their answers. To narrow the gap …

ZINC: a free tool to discover chemistry for biology

JJ Irwin, T Sterling, MM Mysinger… - Journal of chemical …, 2012 - ACS Publications
ZINC is a free public resource for ligand discovery. The database contains over twenty
million commercially available molecules in biologically relevant representations that may be …

Relating protein pharmacology by ligand chemistry

…, BL Roth, BN Armbruster, P Ernsberger, JJ Irwin… - Nature …, 2007 - nature.com
The identification of protein function based on biological information is an area of intense
research. Here we consider a complementary technique that quantitatively groups and relates …

Directory of useful decoys, enhanced (DUD-E): better ligands and decoys for better benchmarking

MM Mysinger, M Carchia, JJ Irwin… - Journal of medicinal …, 2012 - ACS Publications
A key metric to assess molecular docking remains ligand enrichment against challenging
decoys. Whereas the directory of useful decoys (DUD) has been widely used, clear areas for …