User profiles for Jonathan J. Lee

Jonathan Lee

University of Ottawa
Verified email at uottawa.ca
Cited by 6796

[HTML][HTML] TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity

…, D Snead, JJ Lee, JM McCaffery, J Shorter… - Journal of Biological …, 2009 - ASBMB
Non-amyloid, ubiquitinated cytoplasmic inclusions containing TDP-43 and its C-terminal
fragments are pathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motor …

Teledermatology: a review and update

JJ Lee, JC English - American journal of clinical dermatology, 2018 - Springer
Telemedicine is slowly transforming the way in which healthcare is delivered and has the
potential to improve access to subspecialty expertise, reduce healthcare costs, and improve …

Quantitative assessment of multiorgan sequestration of parasites in fatal pediatric cerebral malaria

DA Milner Jr, JJ Lee, C Frantzreb… - The Journal of …, 2015 - academic.oup.com
Children in sub-Saharan Africa continue to acquire and die from cerebral malaria, despite
efforts to control or eliminate the causative agent, Plasmodium falciparum. We present a …

Cervical spine imaging and treatment outcomes in scalp dysesthesia: a retrospective cohort study

JJ Lee, C Morillo-Hernandez, V Agarwal… - Journal of the …, 2023 - ncbi.nlm.nih.gov
Scalp dysesthesia (SD) presents with abnormal scalp sensations in the absence of an
underlying primary dermatologic disorder. Initially attributed to psychiatric disorders, 1 SD …

Perceptions of Community Service in Dermatology Residency Training Programs: A Survey-Based Study of Program Directors, Residents, and Recent Dermatology …

VS Humphrey, BM Patel, JJ Lee, AJ James - Cutis, 2022 - search.ebscohost.com
The article presents a study of program directors, residents, and recent dermatology residency
graduates on the perceptions of community service in dermatology residency training …

An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19

…, BL Hurst, EP Kadar, AS Kalgutkar, JC Lee, J Lee… - Science, 2021 - science.org
The worldwide outbreak of COVID-19 caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has become a global pandemic. Alongside vaccines, antiviral …

[HTML][HTML] Prevention of fat-induced insulin resistance by salicylate

…, JJ Fillmore, Y Chen, I Moore, J Lee… - The Journal of …, 2001 - Am Soc Clin Investig
Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and may involve
fat-induced activation of a serine kinase cascade involving IKK-β. To test this hypothesis, we …

[HTML][HTML] Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

…, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee… - Nature …, 2017 - nature.com
Following uncontrolled proliferation, a subset of primary tumour cells acquires additional
traits/mutations to trigger phenotypic changes that enhance migration and are hypothesized to …

Sensitivity of quantitative EEG for seizure identification in the intensive care unit

…, CD Hahn, MB Westover, JJ Halford, JW Lee… - Neurology, 2016 - AAN Enterprises
Objective: To evaluate the sensitivity of quantitative EEG (QEEG) for electrographic seizure
identification in the intensive care unit (ICU). Methods: Six-hour EEG epochs chosen from 15 …

Building the case for financial education

J Fox, S Bartholomae, J Lee - Journal of consumer affairs, 2005 - Wiley Online Library
The need for financial education among Americans is often demonstrated with alarming rates
of bankruptcy, high consumer debt levels, low savings rates, and other negative outcomes …