User profiles for KELLY GRIMES
Kelly GrimesCincinnati Children's Hospital Verified email at cchmc.org Cited by 605 |
[HTML][HTML] Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy
The thrombospondin (Thbs) family of secreted matricellular proteins are stress- and injury-induced
mediators of cellular attachment dynamics and extracellular matrix protein production. …
mediators of cellular attachment dynamics and extracellular matrix protein production. …
Blue-blocking IOLs: a complete review of the literature
BA Henderson, KJ Grimes - Survey of ophthalmology, 2010 - Elsevier
Intraocular lenses (IOLs) that block both ultraviolet and blue wavelength light (<500 nm)
were introduced in the 1990s. Since then, the potential benefits and harm from blocking blue …
were introduced in the 1990s. Since then, the potential benefits and harm from blocking blue …
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy
…, SC Lin, MA Sargent, KM Grimes… - Proceedings of the …, 2023 - National Acad Sciences
To better understand the genetic basis of heart disease, we identified a variant in the Flightless-I
homolog (FLII) gene that generates a R1243H missense change and predisposes to …
homolog (FLII) gene that generates a R1243H missense change and predisposes to …
[HTML][HTML] ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity
MAPK signaling consists of an array of successively acting kinases. ERK1 and-2 (ERK1/2)
are major components of the greater MAPK cascade that transduce growth factor signaling at …
are major components of the greater MAPK cascade that transduce growth factor signaling at …
MCUb induction protects the heart from postischemic remodeling
Rationale: Mitochondrial Ca 2+ loading augments oxidative metabolism to match functional
demands during times of increased work or injury. However, mitochondrial Ca 2+ overload …
demands during times of increased work or injury. However, mitochondrial Ca 2+ overload …
[HTML][HTML] Age-related changes in the proteostasis network in the brain of the naked mole-rat: implications promoting healthy longevity
…, A Tramutola, A Swomley, J Kirk, K Grimes… - … et Biophysica Acta (BBA …, 2015 - Elsevier
The naked mole-rat (NMR) is the longest-lived rodent and possesses several exceptional
traits: marked cancer resistance, negligible senescence, prolonged genomic integrity, …
traits: marked cancer resistance, negligible senescence, prolonged genomic integrity, …
Establishing consensus on the best practice guidelines for the use of bracing in adolescent idiopathic scoliosis
…, P Bakarania, H Berdishevsky, LA Dolan, K Grimes… - Spine deformity, 2020 - Springer
Study design Survey. Objectives Bracing is the mainstay of conservative treatment in
Adolescent Idiopathic Scoliosis (AIS). The purpose of this study was to establish best practice …
Adolescent Idiopathic Scoliosis (AIS). The purpose of this study was to establish best practice …
Stepwise approach to establishing an ophthalmology wet laboratory
BA Henderson, KJ Grimes, RE Fintelmann… - Journal of Cataract & …, 2009 - Elsevier
Wet laboratories (wet labs) play an increasingly important role in ophthalmology surgical
residency training. We summarize the necessary components in establishing and maintaining a …
residency training. We summarize the necessary components in establishing and maintaining a …
And the beat goes on: maintained cardiovascular function during aging in the longest-lived rodent, the naked mole-rat
KM Grimes, AK Reddy, ML Lindsey… - American Journal of …, 2014 - journals.physiology.org
… *KM Grimes and AK Reddy contributed equally to this work. … *KM Grimes and AK Reddy
contributed equally to this work. … * KM Grimes and AK Reddy contributed equally to this work. …
contributed equally to this work. … * KM Grimes and AK Reddy contributed equally to this work. …
Return on investment in healthcare leadership development programs
…, F Farshidfar, J Lys, G Dickson, K Grimes… - Leadership in Health …, 2018 - emerald.com
Purpose Strong leadership has been shown to foster change, including loyalty, improved
performance and decreased error rates, but there is a dearth of evidence on effectiveness of …
performance and decreased error rates, but there is a dearth of evidence on effectiveness of …