[HTML][HTML] A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
The rat has been used extensively as a model for evaluating chemical toxicities and for
understanding drug mechanisms. However, its transcriptome across multiple organs, or …
understanding drug mechanisms. However, its transcriptome across multiple organs, or …
Leptomeningeal enhancement at 7T in multiple sclerosis: frequency, morphology, and relationship to cortical volume
DM Harrison, KY Wang, J Fiol, K Naunton… - Journal of …, 2017 - Wiley Online Library
BACKGROUND AND PURPOSE Perform an investigation of the frequency and distribution
of leptomeningeal enhancement on postgadolinium magnetization‐prepared FLAIR (…
of leptomeningeal enhancement on postgadolinium magnetization‐prepared FLAIR (…
Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency
…, VL Troung-Le, KA Janes, KY Lin, Y Wang… - Journal of controlled …, 2001 - Elsevier
Chitosan-DNA nanoparticles were prepared using a complex coacervation process. The
important parameters for the nanoparticle synthesis were investigated, including the …
important parameters for the nanoparticle synthesis were investigated, including the …
Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter and gene body methylation in transcriptional regulation
Background DNA methylation is an important type of epigenetic modification involved in
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
gene regulation. Although strong DNA methylation at promoters is widely recognized to be …
Diffuse palmoplantar keratotic papules and melanosis.
The article presents a case study of a 9-year-old boy presented with punctate papules over
the palmoplantar palms and soles. Topics discussed include lamotrigine for the treatment of …
the palmoplantar palms and soles. Topics discussed include lamotrigine for the treatment of …
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
Large intervening non-coding RNAs (lincRNAs) are pervasively transcribed in the genome 1
, 2 , 3 yet their potential involvement in human disease is not well understood 4 , 5 . Recent …
, 2 , 3 yet their potential involvement in human disease is not well understood 4 , 5 . Recent …
Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project
…, S Taing, T Takasaki, D Vafeados, K Voronina, G Wang… - Science, 2010 - science.org
We systematically generated large-scale data sets to improve genome annotation for the
nematode Caenorhabditis elegans, a key model organism. These data sets include …
nematode Caenorhabditis elegans, a key model organism. These data sets include …
Immunogenicity of a DNA vaccine candidate for COVID-19
…, C Qin, AS Brown, M Khoshnejad, N Wang… - Nature …, 2020 - nature.com
The coronavirus family member, SARS-CoV-2 has been identified as the causal agent for
the pandemic viral pneumonia disease, COVID-19. At this time, no vaccine is available to …
the pandemic viral pneumonia disease, COVID-19. At this time, no vaccine is available to …
Architecture of the human regulatory network derived from ENCODE data
…, L Ramirez, TE Reddy, B Reed, M Shi, T Slifer, J Wang… - Nature, 2012 - nature.com
Transcription factors bind in a combinatorial fashion to specify the on-and-off states of genes;
the ensemble of these binding events forms a regulatory network, constituting the wiring …
the ensemble of these binding events forms a regulatory network, constituting the wiring …
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
Over the past decade, great progress has been made in understanding the complexity of
adipose tissue biology and its role in metabolism. This includes new insights into the multiple …
adipose tissue biology and its role in metabolism. This includes new insights into the multiple …