TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections
LW Shen, HJ Mao, YL Wu, Y Tanaka, W Zhang - Biochimie, 2017 - Elsevier
Influenza virus and coronavirus epidemics or pandemics have occurred in succession
worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat …
worldwide throughout the early 21st century. These epidemics or pandemics pose a major threat …
[HTML][HTML] γδ T cells and their potential for immunotherapy
YL Wu, YP Ding, Y Tanaka, LW Shen… - … journal of biological …, 2014 - ncbi.nlm.nih.gov
Vγ9Vδ2 (also termed Vγ2Vδ2) T cells, a major human peripheral blood γδ T cell subset,
recognize microbial (E)-4-hydroxy-3-methylbut-2-enyl diphosphate and endogenous …
recognize microbial (E)-4-hydroxy-3-methylbut-2-enyl diphosphate and endogenous …
[HTML][HTML] Neuroprotective effect of deferoxamine on erastin-induced ferroptosis in primary cortical neurons
…, WY Shen, X Wang, CX Zhao, WX Li… - Neural regeneration …, 2020 - journals.lww.com
The iron chelator deferoxamine has been shown to inhibit ferroptosis in spinal cord injury.
However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell …
However, it is unclear whether deferoxamine directly protects neurons from ferroptotic cell …
Using asphaltene supermolecules derived from coal for the preparation of efficient carbon electrodes for supercapacitors
WH Qu, YB Guo, WZ Shen, WC Li - The Journal of Physical …, 2016 - ACS Publications
Asphaltene supermolecules extracted from coal consist of highly condensed polyaromatic
units and peripheral aliphatic chains, which is a natural source with high carbon content. In …
units and peripheral aliphatic chains, which is a natural source with high carbon content. In …
Prediction of relative displacement for entry roof with weak plane under the effect of mining abutment stress
In coal mining, the entry roof with a weak plane (ERWP) is vulnerable to large relative
displacement, and even caving influenced by the mining stress from the adjacent working face (…
displacement, and even caving influenced by the mining stress from the adjacent working face (…
[HTML][HTML] The impact of artificial intelligence on health equity in oncology: scoping review
Background The field of oncology is at the forefront of advances in artificial intelligence (AI)
in health care, providing an opportunity to examine the early integration of these …
in health care, providing an opportunity to examine the early integration of these …
[HTML][HTML] Inhibition of Influenza A virus propagation by benzoselenoxanthenes stabilizing TMPRSS2 Gene G-quadruplex and hence down-regulating TMPRSS2 …
LW Shen, MQ Qian, K Yu, S Narva, F Yu, YL Wu… - Scientific Reports, 2020 - nature.com
Proteolytic cleavage of influenza A virus (IAV) hemagglutinin by host proteases is crucial for
virus infectivity and spread. The transmembrane serine protease TMPRSS2 was previously …
virus infectivity and spread. The transmembrane serine protease TMPRSS2 was previously …
Diastereoselective Construction of Cyclopropane-Fused Tetrahydroquinolines via a Sequential [4+ 2]/[2+ 1] Annulation Reaction
ZH Wang, LW Shen, KX Xie, Y You, JQ Zhao… - Organic …, 2020 - ACS Publications
A sequential [4 + 2]/[2 + 1] annulation of α-aryl vinylsulfoniums with 2-aminochalcones and 2-(2-aminobenzylidene)-1H-indene-1,3(2H)-dione
is reported that affords a series of …
is reported that affords a series of …
Access to 4-Trifluoromethyl Quinolines via Cu-Catalyzed Annulation Reaction of Ketone Oxime Acetates with ortho-Trifluoroacetyl Anilines under Redox-Neutral …
ZH Wang, LW Shen, P Yang, Y You… - The Journal of …, 2022 - ACS Publications
An efficient Cu-catalyzed annulation reaction of ketone oxime acetates with ortho-trifluoroacetyl
anilines has been disclosed. With the developed protocol, a series of 4-trifluoromethyl …
anilines has been disclosed. With the developed protocol, a series of 4-trifluoromethyl …
Facile synthesis of functional gadolinium-doped CdTe quantum dots for tumor-targeted fluorescence and magnetic resonance dual-modality imaging
F Zhang, TT Sun, Y Zhang, Q Li, C Chai, L Lu… - Journal of materials …, 2014 - pubs.rsc.org
Magnetic quantum dots (MQDs) are an important class of agents for fluorescence (FL)/magnetic
resonance (MR) dual-modal imaging due to their excellent optical and magnetic …
resonance (MR) dual-modal imaging due to their excellent optical and magnetic …