Background Our objective was to develop an instrument to assess the methodological
quality of systematic reviews, building upon previous tools, empirical evidence and expert …

Recent insights in rheumatoid arthritis (RA) necessitated updating the European League
Against Rheumatism (EULAR) RA management recommendations. A large international Task …

Significant progress has been made in outcome measurement procedures for osteoarthritis (OA)
clinical trials, and guidelines have been established by the US Food and Drug …

In this article, the 2010 European League against Rheumatism (EULAR) recommendations
for the management of rheumatoid arthritis (RA) with synthetic and biological disease-…

Objectives To provide an update of the European League Against Rheumatism (EULAR)
rheumatoid arthritis (RA) management recommendations to account for the most recent …

Objective. Trials of rheumatoid arthritis (RA) treatments report the average response in
multiple outcome measures for treated patients. It is more clinically relevant to test whether …

Most systematic reviews rely substantially on the assessment of the methodological quality
of the individual trials. The aim of this study was to obtain consensus among experts about a …

Objective. To develop a set of disease activity measures for use in rheumatoid arthritis (RA)
clinical trials, as well as to recommend specific methods for assessing each outcome …

… Maarten Boers… Maarten Boers … Boers had full access to all of the data in the study
and takes responsibility for the integrity of the data and the accuracy of the data analysis. …

OBJECTIVE: Our purpose was to measure the agreement, reliability, construct validity, and
feasibility of a measurement tool to assess systematic reviews (AMSTAR). STUDY DESIGN …