[HTML][HTML] Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
DN Juurlink, MM Mamdani, DS Lee… - … England Journal of …, 2004 - Mass Medical Soc
Background The Randomized Aldactone Evaluation Study (RALES) demonstrated that
spironolactone significantly improves outcomes in patients with severe heart failure. Use of …
spironolactone significantly improves outcomes in patients with severe heart failure. Use of …
Adherence with statin therapy in elderly patients with and without acute coronary syndromes
CA Jackevicius, M Mamdani, JV Tu - Jama, 2002 - jamanetwork.com
ContextLandmark clinical trials have demonstrated the survival benefits of statins, with benefits
usually starting after 1 to 2 years of treatment. Research prior to these trials of older lipid-…
usually starting after 1 to 2 years of treatment. Research prior to these trials of older lipid-…
Effectiveness of virtual reality using Wii gaming technology in stroke rehabilitation: a pilot randomized clinical trial and proof of principle
Background and Purpose— Hemiparesis resulting in functional limitation of an upper extremity
is common among stroke survivors. Although existing evidence suggests that increasing …
is common among stroke survivors. Although existing evidence suggests that increasing …
Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: a population …
Background Non-selective, non-steroidal anti-inflammatory drugs (NSAIDs) are associated
with an increased risk of congestive heart failure, but little is known about the cardiovascular …
with an increased risk of congestive heart failure, but little is known about the cardiovascular …
IScore: a risk score to predict death early after hospitalization for an acute ischemic stroke
Background— A predictive model of stroke mortality may be useful for clinicians to improve
communication with and care of hospitalized patients. Our aim was to identify predictors of …
communication with and care of hospitalized patients. Our aim was to identify predictors of …
[HTML][HTML] Atrial fibrillation in patients with cryptogenic stroke
Background Atrial fibrillation is a leading preventable cause of recurrent stroke for which
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
early detection and treatment are critical. However, paroxysmal atrial fibrillation is often …
[HTML][HTML] A population-based study of the drug interaction between proton pump inhibitors and clopidogrel
Background: Most proton pump inhibitors inhibit the bioactivation of clopidogrel to its active
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …
metabolite. The clinical significance of this drug interaction is unknown. Methods: We …
Drug-drug interactions among elderly patients hospitalized for drug toxicity
DN Juurlink, M Mamdani, A Kopp, A Laupacis… - Jama, 2003 - jamanetwork.com
ContextDrug-drug interactions are a preventable cause of morbidity and mortality, yet their
consequences in the community are not well characterized.ObjectiveTo determine whether …
consequences in the community are not well characterized.ObjectiveTo determine whether …
Long-term analgesic use after low-risk surgery: a retrospective cohort study
Background This study evaluated the risk of long-term analgesic use after low-risk surgery
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …
in older adults not previously prescribed analgesics. Methods We conducted a retrospective …
Chronic dialysis and death among survivors of acute kidney injury requiring dialysis
Context Severe acute kidney injury among hospitalized patients often necessitates initiation
of short-term dialysis. Little is known about the long-term outcome of those who survive to …
of short-term dialysis. Little is known about the long-term outcome of those who survive to …