Background Optimal treatment and precise classification for anaplastic glioma are needed.
Methods The objective for long-term follow-up of NOA-04 is to optimize the treatment …

Purpose Single center evaluation of the placement accuracy of thoracolumbar pedicle screws
implanted either with fluoroscopy or under CT-navigation using 3D-reconstruction and …

Contemporary brain tumor research focuses on two challenges: First, tumor typing and grading
by analyzing excised tissue is of utmost importance for choosing a therapy. Second, for …

Background Degenerative lumbar spinal stenosis is increasingly being diagnosed in persons
over age 65. In 2011, 55 793 older people with this condition were treated as inpatients in …

Introduction We investigated the incidence of, outcome from and possible risk factors for
readmission to the surgical intensive care unit (ICU) at Friedrich Schiller University Hospital, …

K + channels play an important role in glial cell proliferation and are functionally expressed
in glial tumors. Because voltage-gated K + channel (Kv) subtypes Kv1.3 and Kv1.5 have …

Object In patients who have undergone decompressive craniectomy, autologous bone flap
reinsertion becomes necessary whenever the cerebral situation has consolidated. However, …

OBJECT The complication rate for cranioplasty after decompressive craniectomy is higher
than that after other neurosurgical procedures; aseptic bone resorption is the major long-term …

Background: Intracerebral hemorrhage (ICH) is a life threatening entity, and an early outcome
assessment is mandatory for optimizing therapeutic efforts. Methods: We retrospectively …

Background The optimal management of chronic subdural hematomas remains a challenge.
Twist drill craniotomy or burr hole trephination are considered optimal initial treatments, but …