The balance between local remodeling and accumulation of trabecular bone microdamage
is believed to play an important role in the maintenance of skeletal integrity. However, the …

Synthetic and naturally derived scaffold biomaterials in combination with osteogenic cells or
bioactive factors have the potential to serve as bone graft substitutes. Porous poly(l‐lactide‐…

With age, alterations occurring in bone quality, quantity, and microarchitecture affect the
resistance of trabecular bone to local failure. The clinical implications of these changes are …

The total product life cycle (TPLC) of medical devices has been defined by four stages:
discovery and ideation, regulatory decision, product launch, and postmarket monitoring. …

Several approaches (anterior, posterior, lateral, and transforaminal) are used in lumbar
fusion surgery. However, it is unclear whether one of these approaches has the greatest …

Ultrasound parameters (attenuation, phase velocity, and backscatter), bone mineral density (BMD),
and microarchitectural features were measured on 29 human cancellous calcaneus …

There is a public health need to understand the effects of surface layer thickness and
composition on corrosion in nickel-containing medical devices. To address this knowledge gap, …

Prior to implantation, Nitinol-based transcatheter endovascular devices are subject to a complex
thermo-mechanical pre-strain associated with constraint onto a delivery catheter, device …

Although nitinol is widely used in percutaneous cardiovascular interventions, a causal
relationship between nickel released from implanted cardiovascular devices and adverse …

A major limitation with current assessments of corrosion in metallic medical devices is the lack
of correlation between in-vitro and in-vivo corrosion performance. Therefore, the objective …